Preventing neuraxial administration of tranexamic acid

Beverley A Orser^{1

2

3

4

5}, Sylvia Hyland⁴, Robert Byrick^{2

4}

Affiliations

¹ Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
² Department of Anesthesiology & Pain Medicine, University of Toronto, Toronto, ON, Canada.
³ Department of Physiology, University of Toronto, Toronto, ON, Canada.
⁴ Institute for Safe Medication Practices Canada, Toronto, ON, Canada.
⁵ , Room 3318, Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

Editorial

Beverley A Orser et al. Can J Anaesth. 2023 May.

. 2023 May;70(5):811-816.

doi: 10.1007/s12630-023-02434-1. Epub 2023 Mar 13.

Beverley A Orser^{1

2

3

4

5}, Sylvia Hyland⁴, Robert Byrick^{2

4}

¹ Department of Anesthesia, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
² Department of Anesthesiology & Pain Medicine, University of Toronto, Toronto, ON, Canada.
³ Department of Physiology, University of Toronto, Toronto, ON, Canada.
⁴ Institute for Safe Medication Practices Canada, Toronto, ON, Canada.
⁵ , Room 3318, Medical Sciences Building, 1 King's College Circle, Toronto, ON, M5S 1A8, Canada.

No abstract available

References

1. Pysyk CL, Filteau L. Accidental administration of tranexamic acid into the epidural space: a case report. Can J Anesth 2022; 69: 1169–73. https://doi.org/10.1007/s12630-022-02276-3 - DOI - PubMed
1. Patel S. Accidental infusion of tranexamic acid via a thoracic epidural catheter. Can J Anesth 2023; https://doi.org/10.1007/s12630-023-02435-0 . - DOI - PubMed
1. Patel S, Robertson B, McConachie I. Catastrophic drug errors involving tranexamic acid administered during spinal anaesthesia. Anaesthesia 2019; 74: 904–14. https://doi.org/10.1111/anae.14662 - DOI - PubMed
1. Liu H, Tariq R, Liu GL, Yan H, Kaye AD. Inadvertent intrathecal injections and best practice management. Acta Anaesthesiol Scand 2017; 61: 11–22. https://doi.org/10.1111/aas.12821 - DOI - PubMed
1. Merino JG, Latour LL, Tso A, et al. Blood-brain barrier disruption after cardiac surgery. Am J Neuroradiol 2013; 34: 518–23. https://doi.org/10.3174/ajnr.a3251 - DOI - PubMed - PMC