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. 2023 Mar 1;13(3):1994-2000.
doi: 10.21037/qims-22-311. Epub 2023 Jan 10.

A large leiomyoma of the round ligament: a case description and literature analysis

Linzhen Wei #  1 , Tiansheng Qin #  1 , Juan Chu  2 , Xihui Chong  3 , Wenhua Wang  4 , Ping Li  4
Affiliations

A large leiomyoma of the round ligament: a case description and literature analysis

Linzhen Wei et al. Quant Imaging Med Surg. .
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://qims.amegroups.com/article/view/10.21037/qims-22-311/coif). All authors reported that this work was supported by the Youth Science Foundation of Gansu Province (21JR1RA006), the Natural Science Foundation of Gansu Province of China (21JR1RA012), the Internal Hospital Scientific Research Project of Gansu Province (21GSSYC-10), and the Innovation and Entrepreneurship Talent Project of Lanzhou (2020-RC-52). The authors have no other conflicts of interest to declare.

Figures

Figure 1
Figure 1
Abdominal ultrasound showing a large solid tumor of the left parametrium attached to the uterus (maximum tumor diameter, 11.2 cm).
Figure 2
Figure 2
Magnetic resonance imaging revealed a soft tissue mass 9.6 cm × 6.9 cm × 4.9 cm in size with no pathological lymph nodes. The mass is clearly visible in both coronal and transverse view images. (A) T2 fatsat. (B) T1 in-phase. (C) DWI. (D) ADC. (E) ART. (F) DEL. (G) T2 coronal view. DWI, diffusion weighted imaging; ADC, apparent diffusion coefficient; ART, arterial phase; DEL, delay phase.
Figure 3
Figure 3
Macroscopic and microscopic findings. (A,B) Intraoperative photographs collected at laparoscopy showed that the mass was located in the left round ligament of the uterus. (C) Gross findings showed the central tissue was yellow, solid, and soft. (D-J). Histopathological findings (×20 magnification). (D) Hematoxylin and eosin staining of tumor cells showed a spindle-shaped smooth muscle cell tumor with no necrosis or atypia. Staining by immunohistochemistry (IHC): (E) vimentin expression was positive; (F) H-caldesmon expression was positive; (G) smooth muscle actin (SMA) expression was positive; (H) desmin expression was positive; (I) Ki-67 (positive rate <10%); (J) CKP expression was negative.
See this image and copyright information in PMC

References

    1. Bhatti D, Mandrelle K, Chander A. Leiomyoma of the round ligament in a postmenopausal woman: A rare case report. Int J Gynaecol Obstet 2022;156:585-6. 10.1002/ijgo.13949 - DOI - PubMed
    1. Klingbeil KD, Polcari AM, Azab B, Franceschi D. Large, extra-abdominal leiomyoma of the round ligament with carneous degeneration. BMJ Case Rep 2017;2017:bcr-2017-222454. 10.1136/bcr-2017-222454 - DOI - PMC - PubMed
    1. Vignali M, Bertulessi C, Spreafico C, Busacca M. A large symptomatic leiomyoma of the round ligament. J Minim Invasive Gynecol 2006;13:375-6. 10.1016/j.jmig.2006.03.008 - DOI - PubMed
    1. Grossman SL, Cheung VYT. Round ligament fibroid. J Obstet Gynaecol Can 2007;29:109. 10.1016/S1701-2163(16)32385-4 - DOI - PubMed
    1. Kirkham JC, Nero CJ, Tambouret RH, Yoon SS. Leiomyoma and leiomyosarcoma arising from the round ligament of the uterus. J Am Coll Surg 2008;207:452. 10.1016/j.jamcollsurg.2008.01.068 - DOI - PubMed