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Case Reports
. 2023 Jun 1;42(6):e201-e203.
doi: 10.1097/INF.0000000000003896. Epub 2023 Mar 2.

Severe Bacterial Infection Initially Misdiagnosed as MIS-C: Caution Needed

Anna Stanzelova  1 , Agathe Debray  1 , Slimane Allali  1 , Zahra Belhadjer  2 , Muhamed-Kheir Taha  3 , Jérémie F Cohen  1 , Julie Toubiana  1
Affiliations
Case Reports

Severe Bacterial Infection Initially Misdiagnosed as MIS-C: Caution Needed

Anna Stanzelova et al. Pediatr Infect Dis J. .

Abstract

Working in the era of the novel coronavirus disease 2019 can predispose to cognitive bias. We present a case of life-threatening bacterial infection misdiagnosed as multisystem inflammatory syndrome in children. While multisystem inflammatory syndrome in children-related myocardial dysfunction is now a well-recognized complication of coronavirus disease 2019, a rigorous differential diagnosis approach, notably for infectious etiologies, is paramount.

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Conflict of interest statement

The authors have no funding or conflicts of interest to disclose.

References

    1. Feldstein LR, Rose EB, Horwitz SM, et al.; Overcoming COVID-19 Investigators. Multisystem inflammatory syndrome in U.S. children and adolescents. N Engl J Med. 2020;383:334–346.
    1. Rowley AH. Understanding SARS-CoV-2-related multisystem inflammatory syndrome in children. Nat Rev Immunol. 2020;20:453–454.
    1. Yock-Corrales A, Lenzi J, Ulloa-Gutierrez R, et al. High rates of antibiotic prescriptions in children with COVID-19 or multisystem inflammatory syndrome: a multinational experience in 990 cases from Latin America. Acta Paediatr. 2021;110:1902–1910.
    1. Harwood R, Allin B, Jones CE, et al.; PIMS-TS National Consensus Management Study Group. A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a national Delphi process. Lancet Child Adolesc Health. 2021;5:133–141.
    1. Arola A, Pikkarainen E, Sipila JO, et al. Occurrence and features of childhood myocarditis: a Nationwide Study in Finland. J Am Heart Assoc. 2017;6:e005306.

Publication types

Supplementary concepts