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. 2023 Apr;29(4):848-850.
doi: 10.3201/eid2904.221576. Epub 2023 Mar 14.

Retrospective Screening of Clinical Samples for Monkeypox Virus DNA, California, USA, 2022

Caitlin A Contag, Jacky Lu, Zachary T Renfro, Abraar Karan, Jorge L Salinas, Michelle Khan, Daniel Solis, Malaya K Sahoo, Fumiko Yamamoto, Benjamin A Pinsky

Retrospective Screening of Clinical Samples for Monkeypox Virus DNA, California, USA, 2022

Caitlin A Contag et al. Emerg Infect Dis. 2023 Apr.

Abstract

We retrospectively screened oropharyngeal and rectal swab samples originally collected in California, USA, for Chlamydia trachomatis and Neisseria gonorrhoeae testing for the presence of monkeypox virus DNA. Among 206 patients screened, 17 (8%) had samples with detectable viral DNA. Monkeypox virus testing from mucosal sites should be considered for at-risk patients.

Keywords: United States; chlamydia; gonorrhea; human immunodeficiency virus; monkeypox virus; mpox; orthopoxvirus; sexually transmitted infections; syphilis; viruses; zoonoses.

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Figures

Figure
Figure
Flowchart of retrospective quantitative PCR screening for MPXV in oropharyngeal and rectal swab samples submitted for Chlamydia trachomatis and Neisseria gonorrhoeae testing, California, USA, 2022. Patients with known MPXV infection (n = 12) were diagnosed by quantitative PCR of cutaneous lesions. Patients without known mpox did not have MPXV-positive tests or cutaneous lesions at the time of specimen collection for C. trachomatis and N. gonorrhoeae testing. MPXV, monkeypox virus.
See this image and copyright information in PMC

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