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. 2023 Mar 14;13(1):4210.
doi: 10.1038/s41598-023-31096-8.

National and sub-national burden and trend of type 1 diabetes in 31 provinces of Iran, 1990-2019

Fatemeh Bandarian #  1 , Yeganeh Sharifnejad Tehrani #  2 , Maryam Peimani  3 , Nazli Namazi  4 , Sahar Saeedi Moghaddam  2   5 , Shahnaz Esmaeili  6 , Mohammad-Mahdi Rashidi  2 , Ensieh Nasli Esfahani  7 , Masoud Masinaei  2 , Negar Rezaei  2 , Nazila Rezaei  2 , Farshad Farzadfar  2   8 , Bagher Larijani  9
Affiliations

National and sub-national burden and trend of type 1 diabetes in 31 provinces of Iran, 1990-2019

Fatemeh Bandarian et al. Sci Rep. .

Abstract

The aim of the study was to report the burden of type one diabetes mellitus (T1DM) by sex, age, year, and province in Iran over the past 30 years, according to data provided by the global burden of disease (GBD) study. Incidence, prevalence, death, disability-adjusted life-years (DALYs), years of life lost, and years lived with disability due to T1DM by age groups and sex was reported for 31 provinces of Iran from 1990 to 2019 with their 95% uncertainty intervals (UI). In 2019, national age-standardized incidence (11.0 (95% UI: 8.9-13.5)), prevalence (388.9 (306.1-482.1)), death (0.7 (0.6-0.8)), and DALYs (51.7 (40.9-65.1)) rates per 100,000 wre higher than 1990 except for death. Also, the mortality to incidence ratio reduced in all provinces over time particularly after 2014 as well. GBD data analysis showed that age-standardized incidence and prevalence rates of T1DM have increased, the death rate reduced, and DALYs remained unchanged during the past 30 years in Iran and its 31 provinces. death rate reduced and DALYs remained unchanged during the past 30 years in Iran and its 31 provinces.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Figure 1
Figure 1
Time trend of T1DM burden by all ages number and age-standardized rate by sex in the country from 1990 to 2019.
Figure 2
Figure 2
The map of Iran by the measures of incidence, prevalence, deaths, and DALYs of T1DM in 1990 and 2019 in 31 provinces.
Figure 3
Figure 3
Time trend of age-standardized T1DM burden by SDI quintiles in the country from 1990 to 2019.
Figure 4
Figure 4
National and sub-national percent change in the age-standardized burden of T1DM in 1990–2005 compared to 2005–2019 (a), rates increased more rapidly after vs before 2005. (b) Rates increased more slowly after vs before 2005. (c) rates increased before 2005 but decreased after 2005. (d) rates decreased more rapidly after than before 2005. (e) rates decreased more slowly after than before 2005. (f) rates decreased before 2005 but increased after 2005.
Figure 5
Figure 5
Burden of T1DM in the country by sex and age groups in 1990 and 2019.
Figure 6
Figure 6
Time trend of age-standardized MIR due to T1DM in the country from 1990 to 2019.
Figure 7
Figure 7
Time trend of all ages MIR due to T1DM by SDI quintiles in the country from 1990 to 2019.
See this image and copyright information in PMC

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