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. 2023 Mar 14;11(1):43.
doi: 10.1186/s40478-023-01536-7.

CNS neuroblastoma, FOXR2-activated and its mimics: a relevant panel approach for work-up and accurate diagnosis of this rare neoplasm

Arnault Tauziède-Espariat  1   2 , Dominique Figarella-Branger  3 , Alice Métais  4   5 , Emmanuelle Uro-Coste  6   7   8 , Claude-Alain Maurage  9 , Benoît Lhermitte  10 , Aude Aline-Fardin  11 , Lauren Hasty  4 , Alexandre Vasiljevic  12 , Dan Chiforeanu  13 , Guillaume Chotard  14 , Homa Adle-Biassette  15 , Alexandra Meurgey  16 , Raphaël Saffroy  17 , Delphine Guillemot  18 , Gaëlle Pierron  19 , Philipp Sievers  20   21 , Pascale Varlet  4   5 ; the RENOCLIP-LOC
Affiliations

CNS neuroblastoma, FOXR2-activated and its mimics: a relevant panel approach for work-up and accurate diagnosis of this rare neoplasm

Arnault Tauziède-Espariat et al. Acta Neuropathol Commun. .
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest directly related to the topic of this article.

Figures

Fig. 1
Fig. 1
Flowchart of the study. Different technical panels used: panel 1 (Olig2 and synaptophysin immunopositivities, and vimentin negativity); panel 2 (Olig2, synaptophysin and SOX10 immunopositivities); panel 3 (Olig2, synaptophysin and SOX10 immunopositivities, and vimentin negativity); panel 4 (Olig2, synaptophysin and SOX10 immunopositivities, and vimentin negativity, and 1q gain). The sensitivity and specificity for each panel were: 100 and 71% (panel 1); 100 and 50% (panel 2); 100 and 86% (panel 3); and 100 and 100% (panel 4)
See this image and copyright information in PMC

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