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. 2023 Feb 12;11(1):e22.
doi: 10.22037/aaem.v11i1.1850. eCollection 2023.

Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study

Razan I Nassar  1
Affiliations

Short-term Side Effects of mRNA-based COVID-19 Vaccine Among Jordanian Population; a Cross-sectional Study

Razan I Nassar. Arch Acad Emerg Med. .

Abstract

Introduction: One type of the developed COVID-19 vaccines that received emergency permission and was approved by the food and drug administration (FDA) is the mRNA-based vaccine. The aim of this study is to gather information on the Jordanian population's experience with the vaccine's side effects.

Methods: The study objectives were addressed through a cross-sectional study, which collected information regarding the short-term side effects experienced by the vaccinated individuals within one month following the injection of an mRNA-based COVID-19 vaccine. Data collection was carried out in August 2021. Participants were invited to take part in a self-administered web-based survey created using Google Forms.

Results: Among the study's participants (n= 533), about 56% experienced side effects after the first dose of the mRNA-based COVID-19 vaccine. The most commonly reported side effects after the first dose were sore arm at the injection site (91.6%), and fatigue (83.06%). The female gender was significantly associated with experiencing fatigue, discomfort, chills, and hair loss. Being over 30 years old was significantly associated with experiencing cough. Being a smoker was significantly associated with experiencing shortness of breath and gastrointestinal symptoms.

Conclusion: The mRNA-based COVID-19 vaccine side effects were common, yet, mild, local, and self-limited. The local pain at the injection site was the most commonly reported side effect. Hopefully, the study's findings will aid in lowering resistance to vaccination.

Keywords: COVID-19; COVID-19 vaccines; Coronavirus; Jordan; adverse effects; mRNA vaccine; vaccines.

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Conflict of interest statement

The author declares no relevant conflicts of interest or financial relationships.

Figures

Figure 1
Figure 1
Side effects reported by the study's participants after receiving the first dose (n= 300) and the second dose (n= 267) of the mRNA-based COVID-19 vaccine (the difference was only significant for drowsiness (p = 0.033)).
Figure 2
Figure 2
Association between experiencing side effects and gender, age, and smoking status among the study’s participants
See this image and copyright information in PMC

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