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Comment
. 2023 Mar 14;56(3):469-471.
doi: 10.1016/j.immuni.2023.02.009.

Not immune to stress: LBP's link to depression

Rachel Rahn  1 , Conor Liston  2
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Not immune to stress: LBP's link to depression

Rachel Rahn et al. Immunity. .
Free article

Abstract

Investigators have long suspected a link between inflammation and depression, but the underlying mechanisms are not well understood. Fang et al. report that lipopolysaccharide-binding protein regulates monoamine biosynthesis and might be a missing link and potential therapeutic target for inflammation-associated depressive behaviors.

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Conflict of interest statement

Declaration of interests C.L. is listed as an inventor for Cornell University patent applications on neuroimaging biomarkers for depression that are pending or in preparation. C.L. has served as a scientific advisor or consultant to Compass Pathways PLC, Delix Therapeutics, and Brainify.AI.

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