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Multicenter Study
. 2023 Jun;201(6):1066-1071.
doi: 10.1111/bjh.18754. Epub 2023 Mar 15.

A 16-month-long experience of COVID-19 in allogeneic haematopoietic stem cell transplantation recipients: An SFGM-TC multicentre cohort study

Aliénor Xhaard  1 , Constance Xhaard  2 , Marie-Therese Rubio  3 , Ana Berceanu  4 , Carmen Botella-Garcia  5 , Tereza Coman  6 , Emmanuelle Tavernier  7 , Hélène Labussière-Wallet  8 , Patrice Chevallier  9 , Faezeh Legrand  10 , Anne Thiebaut  11 , Anne-Lise Menard  12 , Catherine Paillard  13 , Sylvain Chantepie  14 , Marie Robin  1 , Stephanie Nguyen  15
Affiliations
Multicenter Study

A 16-month-long experience of COVID-19 in allogeneic haematopoietic stem cell transplantation recipients: An SFGM-TC multicentre cohort study

Aliénor Xhaard et al. Br J Haematol. 2023 Jun.

Abstract

This 16-month-long multicentre retrospective study of 225 allogeneic haematopoietic stem cell transplantation (alloHSCT) recipients with COVID-19 examines risk factors for severity and mortality, describing the successive waves of infections (from March to June 2020 and from August 2020 to June 2021). We confirm the negative role of low respiratory tract disease and immunosuppressive treatment. We highlight significantly lower percentages of severe forms and COVID-19-related mortality during the second wave. Monthly comparative evolution of cases in alloHSCT recipients and in the French population shows a higher number of cases in alloHSCT recipients during the first wave and a decrease from February 2021.

Keywords: COVID-19; SARS-CoV-2; allogeneic hematopoietic stem cell transplantation; infection.

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References

REFERENCES

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