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. 2023 Jan 25;84(2):22m14379.
doi: 10.4088/jcp.22m14379.

Investigating young-adult social outcomes of attention deficit hyperactivity disorder

Lucy Riglin  1 , Andrew Todd  1 , Rachel Blakey  2 , Amy Shakeshaft  1 , Evie Stergiakouli  2 , George Davey Smith  2 , Kate Tilling  2 , Anita Thapar  1
Affiliations

Investigating young-adult social outcomes of attention deficit hyperactivity disorder

Lucy Riglin et al. J Clin Psychiatry. .

Abstract

Objective: Attention Deficit Hyperactivity Disorder (ADHD) is associated with a range of adverse outcomes in adult life. However it is unclear whether the risk pathways to adverse adult outcomes are established during childhood or whether associations are driven by concurrent ADHD symptoms that have persisted to adulthood.

Methods: We examined associations between broadly defined child-limited (remitted) and persistent ADHD (assessed using the ADHD subscale of the Strengths and Difficulties Questionnaire) with social outcomes (low emotional and instrumental support, antisocial behaviour, employment, receipt of state benefits as an indicator of socio-economic disadvantage, homelessness) at age 25 years in a UK longitudinal population sample ALPSAC (the Avon Longitudinal Study of Parents and Children, age 25 data collected between years 2017 and 2018): total N=6439.

Results: Up to 20% of young-people with less favourable social outcomes at age 25 had persistent ADHD. Persistent ADHD was associated with an increased likelihood of being not in education, employment or training (NEET: OR=3.71, 95% CI=2.06 to 6.67, p=1x10-05) and receiving state benefits (OR=2.72, 95% CI=1.62 to 4.57, p=2x10-04) at age 25 years compared to those without ADHD. We did not find strong evidence of associations between child-limited ADHD and social outcomes (NEET OR=1.20, 95% CI=0.54 to 2.69, p=0.65; state benefits OR=1.38, 95% CI=0.76 to 2.51, p=0.29). Persistent ADHD associations with negative social outcomes were observed across family-of-origin income groups, sex and were not explained by comorbidity.

Conclusion: Our findings highlight the importance of continued monitoring and management of ADHD symptoms and related social as well as clinical outcomes across development into adulthood. Future research is needed to identify what factors promote positive social outcomes, including effective treatment of adult ADHD symptoms.

Keywords: ADHD; ALSPAC; persistence; social outcomes; young-adult.

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Figures

Figure 1
Figure 1. ADHD groups for primary analyses
Figure 2
Figure 2. Total number of social outcomes by ADHD group using IPW/MI to account for missing data
Abbreviations: IPW/MI = multiple imputation with inverse probability weighting
See this image and copyright information in PMC

References

    1. Faraone SV, Biederman J, Mick E. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med. 2006 Feb;36(2):159–165. - PubMed
    1. Riglin L, Collishaw S, Thapar AK, et al. Association of Genetic Risk Variants With Attention-Deficit/Hyperactivity Disorder Trajectories in the General Population. JAMA Psychiatry. 2016 Dec 1;73(12):1285–1292. - PMC - PubMed
    1. Garas P, Balazs J. Long-Term Suicide Risk of Children and Adolescents With Attention Deficit and Hyperactivity Disorder—A Systematic Review. Frontiers in psychiatry. 2020;11 - PMC - PubMed
    1. Groenman AP, Janssen TW, Oosterlaan J. Childhood psychiatric disorders as risk factor for subsequent substance abuse: a meta-analysis. Journal of the American Academy of Child & Adolescent Psychiatry. 2017;56(7):556–569. - PubMed
    1. Klein RG, Mannuzza S, Olazagasti MA, et al. Clinical and functional outcome of childhood attention-deficit/hyperactivity disorder 33 years later. Arch Gen Psychiatry. 2012 Dec;69(12):1295–1303. - PMC - PubMed

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