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Case Reports
. 2023 Feb 11;15(2):e34868.
doi: 10.7759/cureus.34868. eCollection 2023 Feb.

Dyke-Davidoff-Masson Syndrome: A Case Report

Venkata Anirudh Chunchu  1 , Nishitha Kommalapati  2 , Sai Sarath Kumar Pemma  1 , Manish Prajwal Mane Manohar  3 , Rahul Reddy Nalamalapu  4
Affiliations
Case Reports

Dyke-Davidoff-Masson Syndrome: A Case Report

Venkata Anirudh Chunchu et al. Cureus. .

Abstract

Dyke-Davidoff-Masson syndrome (DDMS) is a rare neurological entity that is predominantly seen in childhood. Here, we present the case of a 13-year-old girl who was brought to the pediatric ward for general examination with a previous history of seizures, speech difficulty, facial deviation, and progressive left-sided hemiparesis that started at the age of two, followed by delayed developmental milestones. Computed tomography (CT) and magnetic resonance imaging (MRI) of the brain showed right cerebral hemiatrophy, ventriculomegaly, hyperpneumatization of the sinus, the decreased caliber of cortical veins, and skull thickening on the right were all characteristic findings of DDMS. Based on the history, clinical presentation, and imaging findings from CT and MRI, DDMS was confirmed. Identifying DDMS in a clinical setting can be challenging because of low awareness of the condition and varied clinical presentations. Although CT and MRI imaging are the gold standards in diagnosing DDMS, the early manifestations of the disease cannot be well-appreciated on a CT and would likely require an MRI. Since there is no standardized protocol for managing DDMS, the treatment is primarily symptomatic. Early identification and diagnosis of the syndrome are essential to aid the child's mental and physical development through a multidisciplinary approach. There is also a need to improve awareness of DDMS so that the condition can be considered a potential differential diagnosis amongst other similar conditions and does not get misdiagnosed. The lack of a proper protocol for the management of DDMS prompts more research for a better understanding and early identification of the condition.

Keywords: cerebral hemiatrophy; computed tomography (ct); dyke-davidoff-masson syndrome (ddms); hemiplegia; hyperpneumatization; magnetic resonance imaging (mri).

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Axial T2-weighted MRI of the brain demonstrates hemiatrophy changes in the right cerebral hemisphere (white arrow) and hyperpneumatization of the frontal sinus (red arrow).
MRI: magnetic resonance imaging
Figure 2
Figure 2. Coronal T2 FLAIR MRI of the brain demonstrates dilated lateral horn of right ventricle.
MRI: magnetic resonance imaging; FLAIR: fluid-attenuated inversion recovery
Figure 3
Figure 3. Plain CT images of the brain show atrophy of the right cerebral hemisphere (green arrow) with ipsilateral ventriculomegaly (blue arrow) and ipsilateral calvarial thickening (yellow arrow).
CT: computed tomography
Figure 4
Figure 4. Plan CT images of the brain show widening of the sulci and atrophy of the gyri in the right cerebral hemisphere.
CT: computed tomography
See this image and copyright information in PMC

References

    1. Dyke-Davidoff-Masson syndrome: a case report with a literature review. Hamid M, Cherradi S, Satte A, Bourazza A. Radiol Case Rep. 2022;17:2616–2618. - PMC - PubMed
    1. Dyke-Davidoff-Masson syndrome: a case report and review of literature. Younas A, Saim M, Maqsood H, Younus S, Raza MH. Cureus. 2020;12:0. - PMC - PubMed
    1. Dyke-Davidoff-Masson syndrome. Behera MR, Patnaik S, Mohanty AK. J Neurosci Rural Pract. 2012;3:411–413. - PMC - PubMed
    1. Treatment-refractory schizoaffective disorder in a patient with Dyke-Davidoff-Masson syndrome. Amann B, García de la Iglesia C, McKenna P, Pomarol-Clotet E, Sanchez-Guerra M, Orth M. CNS Spectr. 2009;14:36–40. - PubMed
    1. Cerebral hemiatrophy with homolateral hypertrophy of the skull and sinuses. Dyke CG, Davidoff LM, Masson CB. https://cir.nii.ac.jp/crid/1573387449495175552 Surg Gynecol Obstet. 1933;57:588–600.

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