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Case Reports
. 2023 Mar 3;18(5):1784-1787.
doi: 10.1016/j.radcr.2023.01.103. eCollection 2023 May.

Solitary juvenile xanthogranuloma in the parotid gland

Affiliations
Case Reports

Solitary juvenile xanthogranuloma in the parotid gland

Persefoni Margariti et al. Radiol Case Rep. .

Abstract

Juvenile xanthogranuloma (JX) is a non-Langerhans cell histiocytosis. Although precipitating factors remain unclear, it has been described mainly in infancy and early childhood. The giant variant of JX is a rare form that presents in infancy, measures over 2 cm and tends to involute only partly. Herein, we report a very rare localization of a giant JX in the parotid gland, discovered at age 1 month in an infant of a twin pregnancy and studied with ultrasound and magnetic resonance imaging.

Keywords: Children; Juvenile xanthogranuloma; Magnetic resonance imaging; Non-Langerhans cell histiocytosis; Ultrasound.

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Figures

Fig. 1
Fig. 1
Ultrasound of the parotid gland at diagnosis. (A) Shows a heterogenous, mainly hypoechoic intraparotid lesion (39.4 × 23.6 × 33 mm) with peripheral vessels running vertically towards the center. (B) Some intralesional round echogenic spots. (C) Follow-up ultrasound 4 years later shows a smaller intraparotid lesion with dimensions 30 × 21 × 10 mm, without any vessels on color Doppler, but persistent round echogenic spots.
Fig. 2
Fig. 2
MRI of the parotid gland shows an intraparotid lesion. (A) Appearing on T1 weighted. (B) On STIR images with isosignal to the muscles. (C) Presenting an incomplete medial rim of enhancement after contrast administration. MRI, magnetic resonance imaging; STIR, short tau inversion recovery.
Fig. 3
Fig. 3
(A, B) Ultrasound examination performed 4 years after the initial exam shows a much smaller intraparotid lesion (30 × 21 × 10 mm), with no color signal on Doppler exam.

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