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Case Reports
. 2023 Mar 9;85(3):470-472.
doi: 10.1097/MS9.0000000000000181. eCollection 2023 Mar.

Solitary giant neurofibroma of the knee: a case report

Adnane Lachkar  1 , Amine El Farhaoui  1 , Abdeljaouad Najib  1 , Hicham Yacoubi  1
Affiliations
Case Reports

Solitary giant neurofibroma of the knee: a case report

Adnane Lachkar et al. Ann Med Surg (Lond). .

Abstract

Solitary neurofibroma is a rare tumor that occurs particularly in the head and trunk. It is mostly small and rarely exceeds 2 cm.

Case report: A 61-year-old female patient complained about an increasingly extended mass with pain in the right knee for about 14 months. Physical examination reveals a big, solid mass in front of the medial condyle, measuring about 14×12 cm. Tinel's sign was positive on mass percussion. MRI showed a well-circumscribed oval mass with low signal on T1 and high signal on T2-weighted images. A surgical biopsy was performed, and immunohistochemistry confirmed the diagnosis of solitary neurofibroma. Surgical excisions were performed with good outcomes.

Discussion: A giant solitary neurofibroma is exceptional. The knee location is even rarer. Immunohistochemistry is the only way to confirm the diagnosis.

Conclusion: Giant neurofibromas need a complete surgical excision. Until today, there were no other alternative therapies for these tumors.

Keywords: giant neurofibroma; knee; solitary neurofibroma.

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Conflict of interest statement

None.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.

Figures

Figure 1
Figure 1
Clinical presentation of the tumor.
Figure 2
Figure 2
MRI findings (T1- and T2-weighted images).
Figure 3
Figure 3
Intraoperative images (excision of the tumor).
See this image and copyright information in PMC

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