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. 2023 Feb 28:5:100065.
doi: 10.1016/j.sleepx.2023.100065. eCollection 2023 Dec.

Sleep apnea in patients with exacerbated heart failure and overweight

Petar Kalaydzhiev  1   2 , Nikolay Poroyliev  1   2 , Desislava Somleva  1   2 , Radostina Ilieva  1   2 , Dimitar Markov  1   2 , Elena Kinova  1   2 , Asen Goudev  1   2
Affiliations

Sleep apnea in patients with exacerbated heart failure and overweight

Petar Kalaydzhiev et al. Sleep Med X. .

Abstract

Sleep disorders are a common concomitant comorbidity in patients with heart failure. The aims of our study are to determine the incidence and phenotypic characteristics of sleep apnea in overweight patients with exacerbated heart failure and to assess the degree of involvement of systolic and diastolic function impairment in the individual group. From 100 screened patients with heart failure in our department from 2015 to 2017, 61 met the inclusion criteria and participated in the study. 82% (n = 50) of the patients had obstructive sleep apnea (OSA), and 18% (n = 11) had central sleep apnea (CSA). The CSA group had a significantly lower left ventricular ejection fraction (LVEF) than the OSA group (EF% 49.6 ± 8.5 vs 41.8 ± 11.4; p = 0.013). A negative correlation was found between LVEF and the number of central apnea events (r = -0.52; p < 0.001). More frequent hospitalizations for heart failure (HF) and higher mortality rate were found in the CSA group. Screening for sleep apnea in patients with exacerbated heart failure and obesity is necessary for the complex treatment of these patients.

Keywords: Central sleep apnea; Exacerbated heart failure; Obstructive sleep apnea.

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Figures

Fig. 1
Fig. 1
Correlation analysis of the relationship between ejection fraction and number of central sleep apnea events. EF% - ejection fraction %.
Fig. 2
Fig. 2
Survival Functions Kaplan-Meier method for time to first hospitalization for Heart Failure (HF) in months Obstructive sleep disease (OSD); Central sleep disease (CSD).
Fig. 3
Fig. 3
Survival Functions Kaplan-Meier method survival in months. Obstructive sleep disease (OSD); Central sleep disease (CSD).
See this image and copyright information in PMC

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