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Review
. 2023 Aug;70(4):1504-1517.
doi: 10.1002/bab.2455. Epub 2023 Apr 10.

Genus Streptomyces: Recent advances for biotechnological purposes

Apolonio Alves de Lima Júnior  1 , Ednan Cardoso de Sousa  2 , Thales Henrique Barbosa de Oliveira  1 , Raphael Carlos Férrer de Santana  3 , Silvia Katrine Rabelo da Silva  4 , Luana Cassandra Breitenbach Barroso Coelho  1
Affiliations
Review

Genus Streptomyces: Recent advances for biotechnological purposes

Apolonio Alves de Lima Júnior et al. Biotechnol Appl Biochem. 2023 Aug.

Abstract

Actinomycetes are a distinct group of filamentous bacteria. The Streptomyces genus within this group has been extensively studied over the years, with substantial contributions to society and science. This genus is known for its antimicrobial production, as well as antitumor, biopesticide, and immunomodulatory properties. Therefore, the extraordinary plasticity of the Streptomyces genus has inspired new research techniques. The newest way of exploring Streptomyces has comprised the discovery of new natural metabolites and the application of emerging tools such as CRISPR technology in drug discovery. In this narrative review, we explore relevant published literature concerning the ongoing novelties of the Streptomyces genus.

Keywords: CRISPR; Streptomyces genus; actinomycetes; bioactive compounds; biotechnology; nanoparticles.

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References

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