Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 May 1;38(3):257-265.
doi: 10.1097/HCO.0000000000001036. Epub 2023 Mar 2.

Management of pregnancy in left ventricular assist device and heart transplant recipients: a concise review

Affiliations
Review

Management of pregnancy in left ventricular assist device and heart transplant recipients: a concise review

Stefanie Marek-Iannucci et al. Curr Opin Cardiol. .

Abstract

Purpose of review: Women of reproductive age are increasingly undergoing heart transplantation (HT) or left ventricular assist device (LVAD) implantation for advanced heart failure. This review is intended to give an overview of the current state of the art management of pregnancy in patients with LVAD or HT recipients.

Recent findings: Heart transplant recipients are at increased risk for graft rejection, renal dysfunction, preeclampsia and worsening of comorbidities (hypertension and diabetes). Patients with LVAD are at higher risk of thromboembolic events, infections, right ventricular failure and require close surveillance during pregnancy. Preconception counseling must be offered to all women of reproductive age group with HT or LVAD to avoid unplanned pregnancies.

Summary: A multidisciplinary approach with close antepartum and postpartum surveillance is recommended.

PubMed Disclaimer

References

    1. Punnoose LR, Coscia LA, Armenti DP, et al. Pregnancy outcomes in heart transplant recipients. J Heart Lung Transplant 2020; 39:473–480.
    1. Bhagra C, Cherikh W, De Filippis E, et al. Impact of co-morbidities on survival after heart transplant in females of childbearing age: analysis of the International Society for Heart and Lung Transplantation (ISHLT) Registry. Eur Heart J 2022; 43:
    1. Dipchand AI. Current state of pediatric cardiac transplantation. Ann Cardiothorac Surg 2018; 7:31–55.
    1. DeFilippis EM, Haythe J, Farr MA, et al. Practice patterns surrounding pregnancy after heart transplantation. Circ Heart Fail 2020; 13:e006811.
    1. Yadalam AK, Yoo BW, Horton JP, et al. Left ventricular assist devices and pregnancy: systematic review of existing literature and case report. Curr Probl Cardiol 2023; 48:101469.