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. 1987 Nov;40(11):1475-82.
doi: 10.7164/antibiotics.40.1475.

Okilactomycin, a novel antibiotic produced by a Streptomyces species. I. Taxonomy, fermentation, isolation and characterization

H Imai  1 , K Suzuki, M Morioka, Y Numasaki, S Kadota, K Nagai, T Sato, M Iwanami, T Saito
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Free article

Okilactomycin, a novel antibiotic produced by a Streptomyces species. I. Taxonomy, fermentation, isolation and characterization

H Imai et al. J Antibiot (Tokyo). 1987 Nov.
Free article

Abstract

Okilactomycin, a novel antibiotic, was isolated from the culture filtrate of a strain of actinomycetes. The producing organism, strain YP-02908L, was identified as Streptomyces griseoflavus subsp. zamamiensis subsp. nov. The antibiotic was extracted with ethyl acetate and purified by silica gel column chromatography. It was obtained as colorless prisms from a dichloromethane solution. It exhibited weak antimicrobial activity against Ehrlich ascites carcinoma in vivo. The apparent molecular formula of okilactomycin was determined as C24H32O6. It is a new member of the lactone group antibiotics.

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