Magnetic particle based MRI thermometry at 0.2 T and 3 T

Abstract

This study provides insight into the advantages and disadvantages of using ferrite particles embedded in agar gel phantoms as MRI temperature indicators for low-magnetic field scanners. We compare the temperature-dependent intensity of MR images at low-field (0.2 T) to those at high-field (3.0 T). Due to a shorter T₁ relaxation time at low-fields, MRI scanners operating at 0.2 T can use shorter repetition times and achieve a significant T₂^⁎ weighting, resulting in strong temperature-dependent changes of MR image brightness in short acquisition times. Although the signal-to-noise ratio for MR images at 0.2 T MR is much lower than at 3.0 T, it is sufficient to achieve a temperature measurement uncertainty of about ±1.0 °C at 37 °C for a 90 μg/mL concentration of magnetic particles.

Keywords: Low magnetic field scanners; MRI temperature sensors; MRI thermometry; Magnetic particles; Magnetic resonance imaging.