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Review
. 2023 Mar 14:17:667-677.
doi: 10.2147/PPA.S398188. eCollection 2023.

Sleep Disturbance and Immunological Consequences of COVID-19

Jonas Bocek  1 , Jan Prasko #  1   2   3   4 , Samuel Genzor #  5 , Frantisek Hodny #  1 , Jakub Vanek #  1 , Pavol Pobeha #  6 , Kamila Belohradova #  1 , Marie Ociskova #  1   4
Affiliations
Review

Sleep Disturbance and Immunological Consequences of COVID-19

Jonas Bocek et al. Patient Prefer Adherence. .

Abstract

The overarching importance of sleep was further emphasized during the pandemic of COVID-19. The subjects infected by COVID-19 frequently experience sleep disturbances; some are long-lasting problems and decrease the quality of life. Insomnia is the most studied sleep disorder associated with COVID-19. Insomnia affects patients who have experienced an infection and the general population. Good sleep is important in maintaining mental and physical health, including immune system functions. The interconnections between insomnia, the immune system, and COVID-19 are complex. Insomnia triggers numerous immune system dysregulations and makes individuals more vulnerable to respiratory infections. This narrative review overviews the influence of the COVID-19 pandemic on the immune system through sleep disorders.

Keywords: COVID-19; circadian rhythms; immunity; insomnia; mental disorders; sleep deprivation.

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Conflict of interest statement

The authors have no conflict of interest.

Figures

Figure 1
Figure 1
Diagram of the connections between the COVID-19 pandemic and its effects on sleep.
See this image and copyright information in PMC

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