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Editorial
. 2023 Mar 21:14:207-209.
doi: 10.18632/oncotarget.28386.

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

Kamrul Hasan, Thomas J Kipps
Editorial

Impact of cortactin in cancer progression on Wnt5a/ROR1 signaling pathway

Kamrul Hasan et al. Oncotarget. .
No abstract available

Keywords: ROR1; Wnt5a; cortactin; metastasis; migration.

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Conflict of interest statement

CONFLICTS OF INTEREST

Zilovertamab was developed by T.J.K. and his laboratory and licensed by the University of California to Oncternal+ Therapeutics, Inc., and VelosBio, Inc., which provided stock and research funding.

Figures

Figure 1
Figure 1. The molecular mechanism(s) of how Wnt5a signaling could (i) induce ROR1 and cortactin association, tyrosine phosphorylation of cortactin, and activation of RhoA, (ii) enhance F-actin polymerization, and (iii) subsequently promote migration or metastasis of cancer cells.
See this image and copyright information in PMC

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