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Comment
. 2023 Mar 17:15:17588359231156383.
doi: 10.1177/17588359231156383. eCollection 2023.

Why the length of recurrence-free survival or 'lead-times' can be misleading. Comment on: Callesen LB, Takacova T, Hamfjord J, et al. Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis

Steven Sorscher  1
Affiliations
Comment

Why the length of recurrence-free survival or 'lead-times' can be misleading. Comment on: Callesen LB, Takacova T, Hamfjord J, et al. Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis

Steven Sorscher. Ther Adv Med Oncol. .
No abstract available

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Conflict of interest statement

Dr. Sorscher previously was briefly (nine months) employed by Invitae, Corp.

Comment on

References

    1. Callesen LB, Takacova T, Hamfjord J, et al. Circulating DNA in patients undergoing loco-regional treatment of colorectal cancer metastases: a systematic review and meta-analysis. Ther Adv Med Oncol 2022; 14: 1–18. - PMC - PubMed
    1. Tie J, Wang Y, Tomasetti C, et al. Circulating tumor analysis detects minimal residual disease predicts recurrence in patients with stage II colon cancer. Sci Transl Med 2016; 8: 346ra92. - PMC - PubMed
    1. Reinert T, Scholer LV, Thomsen, et al. Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery. Gut 2016; 65: 625–634. - PubMed
    1. Ng SB, Chua C, Ng M, et al. Individualized multiplexed circulating tumour DNA assays for monitoring of tumour presence in patients after colorectal cancer surgery. Sci Rep 2017; 7: 40737. - PMC - PubMed
    1. Chen G, Peng J, Xiao Q, et al. Postoperative circulating tumor DNA as markers of recurrence risk in stages II to III colorectal cancer. J Hematol Oncol 2021; 14: 80. - PMC - PubMed

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