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. 2023 May;14(5):937-945.
doi: 10.1007/s13300-023-01393-6. Epub 2023 Mar 24.

Practical Guide to Glucocorticoid Induced Hyperglycaemia and Diabetes

Hannah L Barker  1 , Deborah Morrison  2 , Andrea Llano  2 , Christopher A R Sainsbury  2 , Gregory C Jones  2
Affiliations

Practical Guide to Glucocorticoid Induced Hyperglycaemia and Diabetes

Hannah L Barker et al. Diabetes Ther. 2023 May.

Abstract

Glucocorticoids, also known as steroids, are a class of anti-inflammatory drugs utilised widely in clinical practice for a variety of conditions. They are associated with a range of side effects including abnormalities of glucose metabolism. Multiple guidelines have been published to illustrate best management of glucocorticoid-induced hyperglycaemia and diabetes in a variety of settings. This article discusses current best clinical practice including diagnosis, investigations and ongoing management of glucocorticoid-induced dysglycaemia in both in- and outpatient settings.

Keywords: Diabetes; Glucocorticoids; Guidelines; Hyperglycaemia; Steroids.

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Conflict of interest statement

Hannah L. Barker, Deborah Morrison, Andrea Llano, Christopher A.R. Sainsbury, Gregory C. Jones have nothing to disclose.

Figures

Fig. 1
Fig. 1
Diagnosis of glucocorticoid-induced hyperglycaemia and diabetes (original diagram adapted from Refs. 4–6)
Fig. 2
Fig. 2
Mechanism of the effect of glucocorticoids on glycaemic control (original diagram adapted from Refs. 5, 7)
Box 1
Box 1
Risk factors for glucocorticoid induced diabetic complications (original diagram adapted from texts 4,6,11)
Fig. 3
Fig. 3
Summary of inpatient recommendations (original diagram adapted from Refs. 4, 14)
Fig. 4
Fig. 4
Summary of outpatient recommendations (original diagram adapted from Refs. 4, 13)
See this image and copyright information in PMC

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