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Comment
. 2023 May;39(5):317-318.
doi: 10.1016/j.pt.2023.03.007. Epub 2023 Mar 23.

Sideways: road to gene-by-gene functional screening in malaria parasites

Thanat Chookajorn  1 , Oliver Billker  2
Affiliations
Comment

Sideways: road to gene-by-gene functional screening in malaria parasites

Thanat Chookajorn et al. Trends Parasitol. 2023 May.

Abstract

Genome-wide screening in apicomplexan species has transformed our understanding of these parasitic protozoa. Kimmel et al. report a 'knock sideways' system and provide a powerful use case for its feasibility in a gene-by-gene screening in Plasmodium falciparum. Carefully deployed, a novel toolkit helps to dissect the biological uniqueness of an important parasite.

Keywords: Apicomplexa; BioID; genetic screening; knock sideways; malaria.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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