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. 2023 Aug;44(8):2667-2677.
doi: 10.1007/s10072-023-06752-6. Epub 2023 Mar 25.

Rehabilitative interventions for impaired handwriting in people with Parkinson's disease: a scoping review

Andrea Gardoni  1   2 , Elisabetta Sarasso  1   2   3   4 , Federica Agosta  1   3   5 , Massimo Filippi  1   3   5   6   7 , Davide Corbetta  8   9
Affiliations

Rehabilitative interventions for impaired handwriting in people with Parkinson's disease: a scoping review

Andrea Gardoni et al. Neurol Sci. 2023 Aug.

Abstract

Background: People with Parkinson's disease (PD) often complain about handwriting difficulties. Currently, there is no consensus on the rehabilitative treatment and outcome measures for handwriting rehabilitation in PD.

Objectives: This study aims to investigate evidence on handwriting rehabilitation in people with PD, examining characteristics of interventions and outcomes.

Methods: A scoping review was conducted according to Arksey and O'Malley's framework and PRISMA-ScR List. We searched electronic databases of PubMed, Physiotherapy Evidence Database, Cochrane Central Register of Controlled Trials, and Embase since inception to January 2023. We included interventional studies assessing the effects of structured rehabilitation programs for impaired handwriting in people with PD. Two reviewers independently selected studies, extracted data, and assessed the risk of bias using the Cochrane Collaboration's tool for assessing Risk of Bias version 2 or the Risk Of Bias In Non-randomized Studies. We performed a narrative analysis on training characteristics and assessed outcomes.

Results: We included eight studies. The risk of bias was generally high. Either handwriting-specific or handwriting-non-specific trainings were proposed, and most studies provided a home-based training. Handwriting-specific training improved writing amplitude while handwriting-non-specific trainings, such as resistance and stretching/relaxation programs, resulted in increased writing speed.

Conclusions: The current knowledge is based on few and heterogeneous studies with high risk of bias. Handwriting-specific training might show potential benefits on handwriting in people with PD. Further high-quality randomized controlled trials are needed to reveal the effect of handwriting training in people with PD on standardized outcome measures. Handwriting-specific training could be combined to resistance training and stretching, which seemed to influence writing performance.

Keywords: Handwriting; Micrographia; Parkinson’s disease; Rehabilitation; Review.

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