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Meta-Analysis
. 2023 Oct;20(8):2964-2972.
doi: 10.1111/iwj.14163. Epub 2023 Mar 25.

Effect of instant surgery compared with traditional management on paediatric complicated acute appendicitis post-surgery wound: A meta-analysis

Xiansheng Cao  1 , Xuejing Geng  2 , Chunlei Zhang  3 , Jun Chen  1 , Chao Zhang  1 , Qi Liu  1 , Tianyu Wu  1 , Lei Li  1
Affiliations
Meta-Analysis

Effect of instant surgery compared with traditional management on paediatric complicated acute appendicitis post-surgery wound: A meta-analysis

Xiansheng Cao et al. Int Wound J. 2023 Oct.

Retraction in

Abstract

A meta-analysis study to assess the influence of instant surgery (IS) compared with conservative therapy (CT) on paediatric complicated acute appendicitis (CAA) post-surgery wounds. A comprehensive literature examination until January 2023 was implemented, and 2098 linked studies were appraised. The picked studies contained 66 674 subjects with paediatric CAA post-surgery wounds in the picked studies' baseline; 64 643 of them were using IS, and 2031 were using CT. The odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of the IS compared with the CT on paediatric CAA post-surgery wounds using the dichotomous and continuous styles and a fixed or random model. The IS had a significantly higher wound infection (OR, 4.97; 95% CI, 2.35-10.54, P < .001) with moderate heterogeneity (I2 = 57%) compared with the CT in a paediatric CAA post-surgery wound. However, no significant difference was found between IS and CT in total antibiotic duration (MD, -5.34; 95% CI,-12.67 to -1.98, P = .15) with high heterogeneity (I2 = 95%) in paediatric CAA post-surgery wounds. The IS had a significantly higher wound infection; however, no significant difference was found in total antibiotic duration compared with the CT in paediatric CAA post-surgery wounds. Although precautions should be taken when commerce with the consequences because most of the studies picked for this meta-analysis had low sample sizes.

Keywords: conservative therapy; instant surgery; paediatric acute appendicitis wound; wound infection.

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Figures

FIGURE 1
FIGURE 1
shows a flowchart of the study process.
FIGURE 2
FIGURE 2
The effect's forest plot of the outcome of IS on wound infection compared with CT in paediatric CAA post‐surgery wounds.
FIGURE 3
FIGURE 3
The effect's forest plot of the outcome of IS on TAD compared with CT in paediatric CAA post‐surgery wounds.
FIGURE 4
FIGURE 4
The outcome's funnel plot of IS on wound infection compared with CT in paediatric CAA post‐surgery wounds.
FIGURE 5
FIGURE 5
The outcome's funnel plot of IS on TAD compared with CT in paediatric CAA post‐surgery wounds.
See this image and copyright information in PMC

References

    1. Vaos G, Dimopoulou A, Gkioka E, Zavras N. Immediate surgery or conservative treatment for complicated acute appendicitis in children? A meta‐analysis. J Pediat Surg. 2019;54(7):1365‐1371. - PubMed
    1. Morrow SE, Newman KD. Current management of appendicitis. Seminars in Pediatric Surgery. Vol 16. Elsevier; 2007:34‐40. - PubMed
    1. Huang L, Yin Y, Yang L, Wang C, Li Y, Zhou Z. Comparison of antibiotic therapy and appendectomy for acute uncomplicated appendicitis in children: a meta‐analysis. JAMA Pediatr. 2017;171(5):426‐434. - PMC - PubMed
    1. Svensson JF, Patkova B, Almström M, et al. Nonoperative treatment with antibiotics versus surgery for acute nonperforated appendicitis in children: a pilot randomized controlled trial. Ann Surg. 2015;261(1):67‐71. - PubMed
    1. Fawley J, Gollin G. Expanded utilization of nonoperative management for complicated appendicitis in children. Langenbecks Arch Surg. 2013;398:463‐466. - PubMed

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