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. 2023 Mar 9:10:1129803.
doi: 10.3389/fsurg.2023.1129803. eCollection 2023.

Management of COVID-19-related post-intubation tracheal stenosis

Affiliations

Management of COVID-19-related post-intubation tracheal stenosis

Serena Conforti et al. Front Surg. .

Abstract

Introduction: The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has affected Italy since the beginning of 2020. Endotracheal intubation, prolonged mechanical ventilation, and tracheostomy are frequently required in patients with severe COVID-19. Tracheal stenosis is a potentially severe condition that can occur as a complication after intubation. The aim of this study was to evaluate the utility and safety of endoscopic and surgical techniques in the treatment of tracheal stenosis related to COVID-19.

Materials and methods: Between June 2020 and May 2022, consecutive patients with tracheal stenosis who were admitted to our surgical department were considered eligible for participation in the study.

Results: A total of 13 patients were included in the study. They consisted of nine women (69%) and four men (31%) with a median age of 57.2 years. We included seven patients with post-tracheostomy tracheal stenosis. Bronchoscopy was performed to identify the type, location, and severity of the stenosis. All patients underwent bronchoscopic dilation and surveillance bronchoscopy at 7 and 30 days after the procedure. We repeated endoscopic treatment in eight patients. Three patients underwent tracheal resection anastomosis. Final follow-up bronchoscopy demonstrated no residual stenosis.

Conclusions: The incidence of and risk factors associated with tracheal stenosis in critically ill patients with COVID-19 are currently unknown. Our experience confirms the efficacy and safety of endoscopic management followed by surgical procedures in cases of relapsed tracheal stenosis.

Keywords: COVID-19; balloon dilatation; endoscopic treatment; tracheal stenosis; tracheal surgery.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
(A) Tracheal stenosis (Myer–Cotton grade II); bronchoscopic examination. (B) Endoscopic result after balloon dilation. (C) Surgical resection of the trachea. (D) Suture of the anterior tracheal wall.

References

    1. COVID-19 Dashboard by the Center for Systems Science and Engineering. 2020 (cited 2020 Jul 2). Available at: https://coronavirus.jhu.edu/map.html.
    1. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. (2020) 395(10223):497–506. 10.1016/S0140-6736(20)30183 - DOI - PMC - PubMed
    1. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CH, He JX, et al. Clinical characteristics of coronavirus disease 2019 in China. N Eng J Med. (2020) 382:1708–20. 10.1056/NEJMoa2002032 - DOI - PMC - PubMed
    1. Phua H, Weng L, Ling L, Egi M, Lim CM, Divatia J, et al. Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations. Lancet Respir Med. (2020) 8:506–17. 10.1016/S2213-2600(20)30161-2 - DOI - PMC - PubMed
    1. Grasselli G, Greco M, Zanella A, Albano G, Antonelli M, Bellani G, et al. Risk factors associated with mortality among patients with COVID 19 in intensive care units in Lombardy, Italy. JAMA Intern Med. (2020) 180:1345–55. 10.1001/jamainternmed.2020.3539 - DOI - PMC - PubMed