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Review
. 2023 Jul;34(8):512-517.
doi: 10.1177/09564624231165547. Epub 2023 Mar 27.

A targeted literature review of health economic analyses of human papillomavirus vaccination from various countries

Hannah A Segal  1 , Nazia Rashid  2
Affiliations
Review

A targeted literature review of health economic analyses of human papillomavirus vaccination from various countries

Hannah A Segal et al. Int J STD AIDS. 2023 Jul.

Abstract

Background: Understanding the cost-effectiveness of the HPV vaccine from a global perspective is important to assess from a policy perspective and to support current and future HPV vaccination programs.

Objectives: The aim of this analysis was to conduct a targeted literature review of published pharmacoeconomic literature on the cost-effectiveness of the HPV vaccine to treat patients in various countries, with a focus on cost-savings and their impact on vaccine recommendations.

Methods: We searched cost-effectiveness studies in HPV published in peer-reviewed literature from 2012 to 2020 using MEDLINE via the PubMed database and Google Scholar.

Results: HPV vaccine cost-effectiveness was found to be greatest in low-income countries where screen programs were not yet in place, additionally, in adolescent males and females. The majority of the economic evaluations viewed the implementation of the HPV vaccine as cost-effective and recommended national HPV vaccination.

Conclusion: The majority of economic studies favored national HPV vaccination for adolescent males and females in various countries. Feasibility of this strategy and implementation remains an open question, in addition to screening coverage rate in countries with no vaccine programs or countries yet to introduce national HPV vaccination.

Keywords: Human papillomavirus vaccine; cervical cancer prevention; economic analysis; literature review.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flow diagram of the included studies by search strategy.
See this image and copyright information in PMC

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