Linking the microbiome to CAR-T cell responses

Zachariah DeFilipp^{1

2}, Marcela V Maus^{3

4}

Affiliations

¹ Hematopoietic Cell Transplant and Cellular Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
² Harvard Medical School, Boston, MA, USA.
³ Harvard Medical School, Boston, MA, USA. mvmaus@mgh.harvard.edu.
⁴ Cellular Immunotherapy Program, Massachusetts General Hospital, Boston, MA, USA. mvmaus@mgh.harvard.edu.

Comment

Zachariah DeFilipp et al. Nat Med. 2023 Apr.

. 2023 Apr;29(4):785-786.

doi: 10.1038/s41591-023-02272-0.

Zachariah DeFilipp^{1

2}, Marcela V Maus^{3

4}

¹ Hematopoietic Cell Transplant and Cellular Therapy Program, Massachusetts General Hospital, Boston, MA, USA.
² Harvard Medical School, Boston, MA, USA.
³ Harvard Medical School, Boston, MA, USA. mvmaus@mgh.harvard.edu.
⁴ Cellular Immunotherapy Program, Massachusetts General Hospital, Boston, MA, USA. mvmaus@mgh.harvard.edu.

No abstract available

Comment on

A non-antibiotic-disrupted gut microbiome is associated with clinical responses to CD19-CAR-T cell cancer immunotherapy.
Stein-Thoeringer CK, Saini NY, Zamir E, Blumenberg V, Schubert ML, Mor U, Fante MA, Schmidt S, Hayase E, Hayase T, Rohrbach R, Chang CC, McDaniel L, Flores I, Gaiser R, Edinger M, Wolff D, Heidenreich M, Strati P, Nair R, Chihara D, Fayad LE, Ahmed S, Iyer SP, Steiner RE, Jain P, Nastoupil LJ, Westin J, Arora R, Wang ML, Turner J, Menges M, Hidalgo-Vargas M, Reid K, Dreger P, Schmitt A, Müller-Tidow C, Locke FL, Davila ML, Champlin RE, Flowers CR, Shpall EJ, Poeck H, Neelapu SS, Schmitt M, Subklewe M, Jain MD, Jenq RR, Elinav E. Stein-Thoeringer CK, et al. Nat Med. 2023 Apr;29(4):906-916. doi: 10.1038/s41591-023-02234-6. Epub 2023 Mar 13. Nat Med. 2023. PMID: 36914893 Free PMC article.

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