Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Jun;49(6):1545-1550.
doi: 10.1111/jog.15640. Epub 2023 Mar 27.

Effects of epidural analgesia at 1 cm cervical dilatation on labor interventions in full-term primigravida: A retrospective cohort study

Shunbin Chen  1 , Siping Ye  1 , Chenhua Wu  1 , Xiufeng Jia  1 , Sangsang Li  1 , Xiaomei Zeng  1
Affiliations

Effects of epidural analgesia at 1 cm cervical dilatation on labor interventions in full-term primigravida: A retrospective cohort study

Shunbin Chen et al. J Obstet Gynaecol Res. 2023 Jun.

Abstract

Objective: This study aimed to investigate the effects of epidural analgesia administered as early as cervical dilatation of 1 cm on labor interventions and maternal and neonatal outcomes.

Methods: This retrospective research recruited 1007 full-term primigravidas, who were distributed to two separate cohorts for eligibility: epidural analgesia 1 (cervical dilatation = 1 cm) and epidural analgesia 2 (cervical dilatation >1 cm). Labor interventions (artificial rupture of membranes and oxytocin administration) and duration of labor were the primary outcomes.

Results: The effect of initiation timing of epidural analgesia on artificial membrane rupture was not statistically significant (adjusted odds ratio [OR]: 0.85 [0.58-1.24], p > 0.05). Less oxytocin was used in the epidural analgesia 2 group compared with the epidural analgesia 1 group (the adjusted OR: 0.68 [0.49-0.95], p < 0.05). There were no significant differences in the median time to latent phase of labor, active phase of labor, second, and third stages of labor (p > 0.05). There were no significant differences in maternal and neonatal outcomes between the epidural analgesia 1 group and the epidural analgesia 2 group.

Conclusion: Epidural analgesia could be administered at cervical dilatation = 1 cm.

Keywords: artificial membrane rupture; cervical dilation; epidural analgesia; labor stage; use of oxytocin.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

REFERENCES

    1. Hawkins JL. Epidural analgesia for labor and delivery. New Engl J Med. 2010;362(16):1503-10.
    1. Bautista L, George RB. Epidural analgesia in labour. CMAJ. 2020;192(19):E509.
    1. Staikou C, Μakris A, Theodoraki K, Τsaroucha A, Douma A, Μoka E, et al. Current practice in obstetric anesthesia and analgesia in public hospitals of Greece: a 2016 National Survey. Balkan Med J. 2018;35(5):394-7.
    1. Traynor AJ, Aragon M, Ghosh D, Choi RS, Dingmann C, Vu Tran Z, et al. Obstetric anesthesia workforce survey: a 30-year update. Anesth Analgesia. 2016;122(6):1939-46.
    1. Blondel B, Coulm B, Bonnet C, Goffinet F, Le Ray C. Trends in perinatal health in metropolitan France from 1995 to 2016: results from the French National Perinatal surveys. J Gynecol Obstet Hum Reprod. 2017;46(10):701-13.

LinkOut - more resources