[Bone formation in bone marrow organ cultures]
- PMID: 3697499
[Bone formation in bone marrow organ cultures]
Abstract
Bone tissue composed of typical bone trabeculae containing ground substance with incorporated osteogenic cells and osteoblast layer was formed in organ cultures of bone marrow obtained from adult mice. Electron microscopic properties of the bone formed in vitro were identical to those of the bone tissue in vivo. The mineralization of the bone took place only in the presence of Na-beta-glycerophosphate in the culture medium.
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