Joint contribution of MC1R and MITF alleles to melanoma risk in the age of polygenic risk scores

William Bruno^{1

2}

Affiliations

¹ Genetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi X, 16132 Genoa, Italy.
² Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.

Editorial

William Bruno. Br J Dermatol. 2023.

. 2023 May 24;188(6):696-697.

doi: 10.1093/bjd/ljad097.

William Bruno^{1

2}

¹ Genetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi X, 16132 Genoa, Italy.
² Department of Internal Medicine and Medical Specialties (DiMI), University of Genoa, Viale Benedetto XV 6, 16132 Genoa, Italy.

No abstract available

Conflict of interest statement

Conflicts of interest the author declares no conflicts of interest.

The MC1R r allele does not increase melanoma risk in MITF E318K carriers.
Wallingford CK, Demeshko A, Krishnakripa AK, Smit DJ, Duffy DL, Betz-Stablein B, Pflugfelder A, Jagirdar K, Holland E, Mann GJ, Primiero CA, Yanes T, Malvehy J, Badenas C, Carrera C, Aguilera P, Olsen CM, Ward SV, Haass NK, Sturm RA, Puig S, Whiteman DC, Law MH, Cust AE, Potrony M, Soyer HP, McInerney-Leo AM. Wallingford CK, et al. Br J Dermatol. 2023 May 24;188(6):770-776. doi: 10.1093/bjd/ljad041. Br J Dermatol. 2023. PMID: 36879448 Free PMC article.