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. 2023 Mar 3;14(3):144.
doi: 10.3390/jfb14030144.

Effect of Propolis on Root Dentine Microhardness When Used as an Intracanal Medicament: An In Vitro Study

Meshal Muhammad Naeem  1 , Huma Sarwar  2 , Aliza Nisar  3 , Shahbaz Ahmed  2 , Juzer Shabbir  4 , Zohaib Khurshid  5   6 , Paulo J Palma  7   8
Affiliations

Effect of Propolis on Root Dentine Microhardness When Used as an Intracanal Medicament: An In Vitro Study

Meshal Muhammad Naeem et al. J Funct Biomater. .

Abstract

Application of intracanal medicaments may affect the physical properties of root dentine. Calcium hydroxide (CH), a gold standard intracanal medicament, has proven to decrease root dentine microhardness. A natural extract, propolis, has been shown to be superior to CH in eradicating endodontic microbes, but its effect on the microhardness of root dentine is still not known. This investigation aims to evaluate the effect of propolis on root dentine microhardness compared to calcium hydroxide. Ninety root discs were randomly divided into three groups and treated with CH, propolis, and a control. A Vickers hardness indentation machine with a load of 200 g and dwell time of 15 s at 24 h, 3, and 7 days was used for microhardness testing. ANOVA and Tukey's post hoc test were used for statistical analysis. A progressive decrease in microhardness values was observed in CH (p < 0.01), whereas a progressive increase was observed in the propolis group (p < 0.01). At 7 days, propolis demonstrated the highest microhardness value (64.43 ± 1.69), whereas CH demonstrated the lowest value (48.46 ± 1.60). The root dentine microhardness increased over time when propolis was applied, while it decreased over time after application of CH on root dentine sections.

Keywords: calcium hydroxide; dentine microhardness; intracanal medicament; propolis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Diagrammatic representation of root dentine discs’ preparation methodology.
Figure 2
Figure 2
Flow diagram demonstrating a summary of the methodology for the assessment of Vickers hardness of root sections.
Figure 3
Figure 3
Mean comparison of microhardness values among experimental groups at different time intervals.
See this image and copyright information in PMC

References

    1. Robledo J.G., Farkas M.P., Rodríguez P.A. Root Canal System Variation in Mandibular Second Molar: Middle-Mesial Canal. Open J. Stomatol. 2023;13:25–31. doi: 10.4236/ojst.2023.131003. - DOI
    1. Haapasalo M., Shen Y.A., Ricucci D. Reasons for persistent and emerging post-treatment endodontic disease. Endod. Topics. 2008;18:31–50. doi: 10.1111/j.1601-1546.2011.00256.x. - DOI
    1. Shabbir J., Khurshid Z., Qazi F., Sarwar H., Afaq H., Salman S., Adanir N. Effect of different host-related factors on postoperative endodontic pain in necrotic teeth dressed with interappointment intracanal medicaments: A multicomparison study. Eur. J. Dent. 2021;15:152–157. doi: 10.1055/s-0040-1721909. - DOI - PMC - PubMed
    1. Kumar A., Tamanna S., Iftekhar H. Intracanal medicaments–Their use in modern endodontics: A narrative review. J. Oral Res. Rev. 2019;11:94.
    1. Ordinola-Zapata R., Noblett W.C., Perez-Ron A., Ye Z., Vera J. Present status and future directions of intracanal medicaments. Int. Endod. J. 2022;55:613. doi: 10.1111/iej.13731. - DOI - PMC - PubMed