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. 2023 Aug 22;101(8):369-370.
doi: 10.1212/WNL.0000000000207244. Epub 2023 Mar 28.

CNS T-Cell Lymphoma Many Years After Hemophagocytic Lymphohistiocytosis

Lauren Lu  1 , Agnes Zhu  1 , Christopher Y Itoh  1 , Ryan P Coburn  1 , Rafid Mustafa  2
Affiliations

CNS T-Cell Lymphoma Many Years After Hemophagocytic Lymphohistiocytosis

Lauren Lu et al. Neurology. .
No abstract available

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Conflict of interest statement

The authors report no relevant disclosures. Go to Neurology.org/N for full disclosures.

Figures

Figure
Figure. Cutaneous and Imaging Findings in T-Cell Lymphoma
Periorbital and perioral swelling (A and B); an MRI of the brain demonstrating a T2-hyperintense left parietal lesion and chronic right arachnoid cyst (C), with heterogeneous enhancement (D), and notable blooming or susceptibility artifact on susceptibility-weighted sequences from the paramagnetic hemosiderin in the associated blood products (E); fluorodeoxyglucose-PET demonstrating hypermetabolic activity throughout the subcutaneous facial lesions (F, arrow) and right internal abdominal oblique muscle (G, arrow); an MRI of the brain demonstrating reduction in size (H) and enhancement (I) of the left parietal lesion 2 months after treatment with high-dose methotrexate and temozolomide.
See this image and copyright information in PMC

References

    1. George MR. Hemophagocytic lymphohistiocytosis: review of etiologies and management. J Blood Med. 2014; 5:69-86. - PMC - PubMed
    1. Han AR, Lee HR, Park BB, et al. . Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome. Ann Hematol. 2007; 86(7):493-498. - PubMed

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