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Review
. 2023 Mar 1;12(3):611.
doi: 10.3390/antiox12030611.

Vitamins and Radioprotective Effect: A Review

Inés Lledó  1 , Blanca Ibáñez  1 , Ana Melero  2 , Alegría Montoro  3   4 , Juan F Merino-Torres  5   6   7 , Nadia San Onofre  1   8 , Jose M Soriano  1   5
Affiliations
Review

Vitamins and Radioprotective Effect: A Review

Inés Lledó et al. Antioxidants (Basel). .

Abstract

The radioprotective effect ex vivo, in vitro and in vivo of vitamins was reviewed using PubMed and Embase and conducted according to the PRISMA statement. A total of 38 articles were included in this review, which includes the radioprotective effect of vitamins from ex vivo, in vitro and in vivo studies. Vitamins A, C, D and E were used alone, in combination or with other nutritional and non-nutritional compounds. The use of vitamins in natural form or supplementation can be useful to reduce the radiation effect in the body, organs and/or cells. Only four (A, C, D and E) out of thirteen vitamins have been detected with radioprotective properties being mainly vitamin E followed by vitamin C, A and D.

Keywords: antioxidants; radiation; radioprotection; vitamins.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flow diagram [7].
See this image and copyright information in PMC

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