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Review
. 2023 Mar 8;15(6):1671.
doi: 10.3390/cancers15061671.

Exercise Training in Elderly Cancer Patients: A Systematic Review

Francesco Giallauria  1   2 , Crescenzo Testa  3 , Gianluigi Cuomo  1 , Anna Di Lorenzo  1 , Elio Venturini  4 , Fulvio Lauretani  3   5 , Marcello Giuseppe Maggio  3   5 , Gabriella Iannuzzo  6 , Carlo Vigorito  1
Affiliations
Review

Exercise Training in Elderly Cancer Patients: A Systematic Review

Francesco Giallauria et al. Cancers (Basel). .

Abstract

Due to the aging of the population, in 70% of cases, a new cancer diagnosis equals a cancer diagnosis in a geriatric patient. In this population, beyond the concept of mortality and morbidity, functional capacity, disability, and quality of life remain crucial. In fact, when the functional status is preserved, the pathogenetic curve towards disability will stop or even regress. The present systematic review investigated the effectiveness of physical exercise, as part of a holistic assessment of the patient, for preventing disability and improving the patient's quality of life, and partially reducing all-cause mortality. This evidence must point towards decentralization of care by implementing the development of rehabilitation programs for elderly cancer patients either before or after anti-cancer therapy.

Keywords: biology of exercise; cancer; cardiac rehabilitation; cardio-oncology; cardiotoxicity; elderly; exercise training; frailty; prehabilitation; quality of life; rehabilitation.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Exercise is effective in counteracting all the mechanisms of action responsible for the transformation of a normal cell into a cancer cell.
Figure 2
Figure 2
PRISMA diagram of selected studies.
Figure 3
Figure 3
Risk of Bias of the included studies according to the ROB2 tool.
See this image and copyright information in PMC

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