Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Mar 16;15(6):1804.
doi: 10.3390/cancers15061804.

Surgical Approach in Metastatic Renal Cell Carcinoma: A Literature Review

Milena Matuszczak  1 , Adam Kiljańczyk  1 , Maciej Salagierski  1
Affiliations
Review

Surgical Approach in Metastatic Renal Cell Carcinoma: A Literature Review

Milena Matuszczak et al. Cancers (Basel). .

Abstract

The treatment of metastatic renal cell carcinoma has undergone considerable advances in the last two decades. Cytoreductive nephrectomy and metastasectomy retains a role in patients with a limited metastatic burden. The choice of optimal treatment regimen remains a matter of debate. The article summarises the current role of surgery in metastatic kidney cancer.

Keywords: kidney cancer; metastases; surgery.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Most common sites of metastases in RCC.
Figure 2
Figure 2
Selected prognostic factors of RCC. NLR—neutrophil to lymphocyte ratio, LDH—lactate dehydrogenase.
See this image and copyright information in PMC

References

    1. Sung H., Ferlay J., Siegel R.L., Laversanne M., Soerjomataram I., Jemal A., Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J. Clin. 2021;71:209–249. doi: 10.3322/caac.21660. - DOI - PubMed
    1. Siegel R.L., Miller K.D., Fuchs H.E., Jemal A. Cancer statistics. CA Cancer J. Clin. 2022;72:7–33. doi: 10.3322/caac.21708. - DOI - PubMed
    1. Yuan S.-M. Surgical treatment of renal cell carcinoma with inferior vena cava tumor thrombus. Surg. Today. 2022;52:1125–1133. doi: 10.1007/s00595-021-02429-9. - DOI - PubMed
    1. Benhaim R., Oussoultzoglou E., Saeedi Y., Mouracade P., Bachellier P., Lang H. Pancreatic Metastasis from Clear Cell Renal Cell Carcinoma: Outcome of an Aggressive Approach. Urology. 2015;85:135–140. doi: 10.1016/j.urology.2014.09.034. - DOI - PubMed
    1. Pantuck A.J., Zisman A., Belldegrun A.S. The changing natural history of renal cell carcinoma. J. Urol. 2001;166:1611–1623. doi: 10.1016/S0022-5347(05)65640-6. - DOI - PubMed

LinkOut - more resources