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Review
. 2023 Mar 1;13(3):460.
doi: 10.3390/jpm13030460.

Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review

Ahmad Bairqdar  1 , Dinara Ivanoshchuk  1   2 , Elena Shakhtshneider  1   2
Affiliations
Review

Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review

Ahmad Bairqdar et al. J Pers Med. .

Abstract

The high prevalence of obesity and of its associated diseases is a major problem worldwide. Genetic predisposition and the influence of environmental factors contribute to the development of obesity. Changes in the structure and functional activity of genes encoding adipocytokines are involved in the predisposition to weight gain and obesity. In this review, variants in genes associated with adipocyte function are examined, as are variants in genes associated with metabolic aberrations and the accompanying disorders in visceral obesity.

Keywords: adipocyte; gene; obesity.

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Conflict of interest statement

The authors declare that they have no conflict of interest.

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