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. 1979 Feb;20(1):61-8.
doi: 10.1111/j.1528-1157.1979.tb04776.x.

The delayed effect of sodium valproate on the photoconvulsive response in man

The delayed effect of sodium valproate on the photoconvulsive response in man

A J Rowan et al. Epilepsia. 1979 Feb.

Abstract

The acute effect of a single oral dose of sodium valproate on the photoconvulsive response has been studied. In 7 of 9 patients naive to this drug photosensitivity was abolished or reduced. A similar effect was seen in only 2 of 7 already receiving chronic sodium valproate therapy. The effect appeared 1 to 5 hr (mean, 3 hr) after attainment of peak sodium valproate concentration and lasted up to 5 days.

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