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. 2023 Mar 10;13(6):1002.
doi: 10.3390/nano13061002.

3D Nanocomposite with High Aspect Ratio Based on Polyaniline Decorated with Silver NPs: Synthesis and Application as Electrochemical Glucose Sensor

Anna A Vasileva  1 , Daria V Mamonova  1 , Vladimir Mikhailovskii  2 , Yuri V Petrov  3 , Yana G Toropova  4 , Ilya E Kolesnikov  5 , Gerd Leuchs  6   7 , Alina A Manshina  1
Affiliations

3D Nanocomposite with High Aspect Ratio Based on Polyaniline Decorated with Silver NPs: Synthesis and Application as Electrochemical Glucose Sensor

Anna A Vasileva et al. Nanomaterials (Basel). .

Abstract

In this paper, we present a new methodology for creating 3D ordered porous nanocomposites based on anodic aluminum oxide template with polyaniline (PANI) and silver NPs. The approach includes in situ synthesis of polyaniline on templates of anodic aluminum oxide nanomembranes and laser-induced deposition (LID) of Ag NPs directly on the pore walls. The proposed method allows for the formation of structures with a high aspect ratio of the pores, topological ordering and uniformity of properties throughout the sample, and a high specific surface area. For the developed structures, we demonstrated their effectiveness as non-enzymatic electrochemical sensors on glucose in a concentration range crucial for medical applications. The obtained systems possess high potential for miniaturization and were applied to glucose detection in real objects-laboratory rat blood plasma.

Keywords: anodic aluminum oxide; glucose sensor; laser-induced deposition; polyaniline.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic presentation of AAO/PANI/Ag nanocomposite synthesis procedure; (a) PANI synthesis on AAO template; (b) laser-induced deposition of Ag NPs on 3D PANI.
Figure 2
Figure 2
Raman spectra of PANI on 2D and 3D substrates (cover slips and AAO membranes, respectively).
Figure 3
Figure 3
SEM data for AAO/PANI with 3D architecture obtained (a) without centrifugation; (b) with centrifugation.
Figure 4
Figure 4
Sample AAO/PANI/Ag; (a) SEM data, top view, secondary electrons detector; (b) SEM data, top view, backscattered electrons detector; (c) SEM data, cross view, secondary electrons detector; (d) SEM data, cross view, backscattered electrons detector; (e); (f) EDX signal of silver distribution along the line.
Figure 5
Figure 5
Raman spectra of methanol (black), silver benzoate solution in methanol before exposition under laser irradiation (red), and after exposition under laser irradiation (blue).
Figure 6
Figure 6
(a) CVA measured in the presence of different concentrations of glucose, third cycle; (b) calibration curve.
Figure 7
Figure 7
Impedance spectroscopy data. (a) In the absence of glucose, equivalent circuit inserted; (b) in the presence of 5 mM glucose.
Figure 8
Figure 8
CV for glucose detection in rat blood plasma on AAO/PANI/Ag nanocomposite.
See this image and copyright information in PMC

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