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Review
. 2023 Jan 14;44(1):72-74.
doi: 10.3760/cma.j.issn.0253-2727.2023.01.014.

[Low-oxygen-affinity hemoglobinopathy Hemoglobin Sunshine Seth: a case report and literature review]

[Article in Chinese]
L Chang  1 , C Y Wang  1 , Z H Li  1 , D B Zhou  1 , X X Cao  1
Affiliations
Review

[Low-oxygen-affinity hemoglobinopathy Hemoglobin Sunshine Seth: a case report and literature review]

[Article in Chinese]
L Chang et al. Zhonghua Xue Ye Xue Za Zhi. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

利益冲突 所有作者声明无利益冲突

Figures

图1
图1. 血红蛋白病Hb Sunshine Seth患者全外显子测序结果（箭头所示为突变位点）
图2
图2. 血红蛋白病Hb Sunshine Seth患者家系图
注 ↗：先证者；■、●：有临床表现（紫绀、血氧下降）男性、女性；□、○：无临床表现男性、女性；*：基因检测阳性；/：死亡
See this image and copyright information in PMC

References

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    1. Perutz MF. Structure and mechanism of hemoglobin[J] Br Med Bull. 1976;32(3):195–208. doi: 10.1093/oxfordjournals.bmb.a071363. - DOI - PubMed
    1. Monod J, Wyman J, Changeux JP. On the nature of allosteric transitions: a plausible model[J] J Mol Biol. 1965;12:88–118. doi: 10.1016/s0022-2836(65)80285-6. - DOI - PubMed
    1. Poyart C, Schaad O, Kister J, et al. Hemoglobin Saint Mandé [beta 102 (G4) Asn----Tyr]. Functional studies and structural modeling reveal an altered T state[J] Eur J Biochem. 1990;194(2):343–348. doi: 10.1111/j.1432-1033.1990.tb15624.x. - DOI - PubMed
    1. Heidenreich LS, Oliveira JL, Holmberg PJ, et al. Hemoglobin Sunshine Seth: A Case Report of Low-Oxygen-Affinity Hemoglobinopathy[J] Case Rep Pediatr. 2020;2020:2853531. doi: 10.1155/2020/2853531. - DOI - PMC - PubMed