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Review
. 2023 May;90(5):501-509.
doi: 10.1007/s12098-023-04545-5. Epub 2023 Mar 29.

Advances in Extracorporeal Support Technologies in Critically Ill Children

Mahsun Yuerek  1 , Benjamin W Kozyak  2 , Venkat R Shankar  2
Affiliations
Review

Advances in Extracorporeal Support Technologies in Critically Ill Children

Mahsun Yuerek et al. Indian J Pediatr. 2023 May.

Abstract

The field of pediatric heart failure is evolving, and the patient population is growing as survival after complex congenital heart surgeries is improving. Mechanical circulatory support and extracorporeal respiratory support in critically ill children has progressed to a mainstay rescue modality in pediatric intensive care medicine. The need for mechanical circulatory support is growing, since the number of organ donors does not meet the necessity. This article aims to review the current state of available mechanical circulatory and respiratory support systems in acute care pediatrics, with an emphasis on the literature discussing the challenges associated with these complex support modalities.

Keywords: Extracorporeal membrane oxygenation; Heart failure; Intensive care medicine; Mechanical circulatory support; Ventricular assist device.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
a TandemHeart blood pump; b Impella; c Rotaflow blood pump; d CentriMag and PediMag blood pumps; e HeartMate3; f Berlin Heart EXCOR blood pump
Fig. 2
Fig. 2
Decision making algorithm. BSA Body surface area, CPB Cardiopulmonary bypass, HCM Hypertrophic cardiomyopathy, VAD Ventricular assist device, VA ECMO Venoarterial extracorporeal membrane oxygenation, VV-ECMO Venovenous extracorporeal membrane oxygenation, Wk Week
See this image and copyright information in PMC

References

    1. Edelson JB, Huang Y, Griffis H, et al. The influence of mechanical circulatory support on post-transplant outcomes in pediatric patients: A multicenter study from the International Society for Heart and Lung Transplantation (ISHLT) Registry. J Heart Lung Transplant. 2021;40:1443–53. doi: 10.1016/j.healun.2021.06.003. - DOI - PubMed
    1. Wehman B, Stafford KA, Bittle GJ, et al. Modern outcomes of mechanical circulatory support as a bridge to pediatric heart transplantation. Ann Thorac Surg. 2016;101:2321–7. doi: 10.1016/j.athoracsur.2015.12.003. - DOI - PMC - PubMed
    1. Hill JD, O'Brien TG, Murray JJ, et al. Prolonged extracorporeal oxygenation for acute post-traumatic respiratory failure (shock-lung syndrome). Use of the Bramson membrane lung. N Engl J Med. 1972;286:629–34. - PubMed
    1. Hill JD, De Leval MR, Fallat RJ, et al. Acute respiratory insufficiency. Treatment with prolonged extracorporeal oxygenation. J Thorac Cardiovasc Surg. 1972;64:551–62. - PubMed
    1. Zapol W, Pontoppidan H, McCullough N, Schmidt V, Bland J, Kitz R. Clinical membrane lung support for acute respiratory insufficiency. Trans Am Soc Artif Intern Organs. 1972;18(553–60):562. - PubMed

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