Endemic or regionally limited bacterial and viral infections in haematopoietic stem-cell transplantation recipients: a Worldwide Network for Blood and Marrow Transplantation (WBMT) Review

Ibrahim N Muhsen¹, Sebastian Galeano², Dietger Niederwieser³, Mickey B C Koh⁴, Per Ljungman⁵, Clarisse M Machado⁶, Mohamed A Kharfan-Dabaja⁷, Rafael de la Camara⁸, Yoshihisa Kodera⁹, Jeff Szer¹⁰, Walid Rasheed¹¹, Simone Cesaro¹², Shahrukh K Hashmi¹³, Adriana Seber¹⁴, Yoshiko Atsuta¹⁵, Mostafa F Mohammed Saleh¹¹, Alok Srivastava¹⁶, Jan Styczynski¹⁷, Abdulrahman Alrajhi¹⁸, Reem Almaghrabi¹⁹, Muhammad Bilal Abid²⁰, Roy F Chemaly²¹, Usama Gergis²², Eolia Brissot²³, Riad El Fakih¹¹, Marcie Riches²⁴, Malgorzata Mikulska²⁵, Nina Worel²⁶, Daniel Weisdorf²⁷, Hildegard Greinix²⁸, Catherine Cordonnier²⁹, Mahmoud Aljurf¹¹

Affiliations

¹ Section of Hematology and Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: ibrahim.muhsen@bcm.edu.
² Hematology Department, British Hospital, Montevideo, Uruguay.
³ Division of Hematology and Medical Oncology, University of Leipzig, Leipzig, Germany; Lithuanian University of Health Sciences Kauno Klinikos, Lithuania; Aichi Medical University School of Medicine, Nagakute, Japan.
⁴ Infection and Immunity Clinical Academic Group, University of London and Department of Haematology, St George's Hospital and Medical School, London, UK; Cell Therapy Facility, Blood Services Group, Health Sciences Authority, Singapore.
⁵ Department of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska University Hospital Huddinge, Karolinska Comprehensive Cancer Center, Stockholm, Sweden; Division of Hematology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
⁶ Virology Laboratory Institute of Tropical Medicine-University of São Paulo Medical School, São Paulo, Brazil; HCT Program-Hospital Amaral Carvalho, Jahu, Brazil.
⁷ Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA.
⁸ Department of Hematology, Hospital de la Princesa, Madrid, Spain.
⁹ Center for Hematopoietic Stem Cell Transplantation, Aichi Medical University Hospital, Nagakute, Japan.
¹⁰ Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
¹¹ Adult Hematology and Stem Cell Transplant, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
¹² Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
¹³ Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Department of Medicine, Sheikh Shakbout Medical City, Abu Dhabi, United Arab Emirates; College of Medicine & Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
¹⁴ Hospital Samaritano Higienópolis and Graacc - Unifesp, São Paulo, Brazil.
¹⁵ Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan; Department of Registry Science for Transplant and Cellular Therapy, Nagakute, Japan.
¹⁶ Department of Hematology, Christian Medical College, Vellore, India.
¹⁷ Department of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz, Poland.
¹⁸ Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
¹⁹ Organ Transplantation Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
²⁰ Divisions of Hematology/Oncology & Infectious Diseases, BMT & Cellular Therapy Program, Milwaukee, WI, USA.
²¹ Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
²² Sidney Kimmel Cancer Center, Philadelphia, PA, USA.
²³ Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France.
²⁴ Division of Hematology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
²⁵ Division of Infectious Diseases, DISSAL, University of Genova, Italy and IRCCS Ospedale Policlinico San Martino, Genova, Italy.
²⁶ Department of Transfusion Medicine and Cell Therapy, Medical University of Vienna, Vienna, Austria.
²⁷ Division of Hematology, Oncology and Transplantation, University of Minnesota, MN, USA.
²⁸ Medical University Graz, Division of Hematology, Graz, Austria.
²⁹ Haematology Department, Henri Mondor Hospital and University Paris-Est-Créteil, Créteil, France.

PMID: 36990623
DOI: 10.1016/S2352-3026(23)00032-7

Review

Endemic or regionally limited bacterial and viral infections in haematopoietic stem-cell transplantation recipients: a Worldwide Network for Blood and Marrow Transplantation (WBMT) Review

Ibrahim N Muhsen et al. Lancet Haematol. 2023 Apr.

. 2023 Apr;10(4):e284-e294.

doi: 10.1016/S2352-3026(23)00032-7.

Authors

Affiliations

¹ Section of Hematology and Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address: ibrahim.muhsen@bcm.edu.
² Hematology Department, British Hospital, Montevideo, Uruguay.
³ Division of Hematology and Medical Oncology, University of Leipzig, Leipzig, Germany; Lithuanian University of Health Sciences Kauno Klinikos, Lithuania; Aichi Medical University School of Medicine, Nagakute, Japan.
⁴ Infection and Immunity Clinical Academic Group, University of London and Department of Haematology, St George's Hospital and Medical School, London, UK; Cell Therapy Facility, Blood Services Group, Health Sciences Authority, Singapore.
⁵ Department of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska University Hospital Huddinge, Karolinska Comprehensive Cancer Center, Stockholm, Sweden; Division of Hematology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
⁶ Virology Laboratory Institute of Tropical Medicine-University of São Paulo Medical School, São Paulo, Brazil; HCT Program-Hospital Amaral Carvalho, Jahu, Brazil.
⁷ Division of Hematology-Oncology, Mayo Clinic, Jacksonville, FL, USA.
⁸ Department of Hematology, Hospital de la Princesa, Madrid, Spain.
⁹ Center for Hematopoietic Stem Cell Transplantation, Aichi Medical University Hospital, Nagakute, Japan.
¹⁰ Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
¹¹ Adult Hematology and Stem Cell Transplant, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
¹² Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata Verona, Verona, Italy.
¹³ Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA; Department of Medicine, Sheikh Shakbout Medical City, Abu Dhabi, United Arab Emirates; College of Medicine & Health Sciences, Khalifa University, Abu Dhabi, United Arab Emirates.
¹⁴ Hospital Samaritano Higienópolis and Graacc - Unifesp, São Paulo, Brazil.
¹⁵ Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan; Department of Registry Science for Transplant and Cellular Therapy, Nagakute, Japan.
¹⁶ Department of Hematology, Christian Medical College, Vellore, India.
¹⁷ Department of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz, Poland.
¹⁸ Department of Medicine, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
¹⁹ Organ Transplantation Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
²⁰ Divisions of Hematology/Oncology & Infectious Diseases, BMT & Cellular Therapy Program, Milwaukee, WI, USA.
²¹ Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
²² Sidney Kimmel Cancer Center, Philadelphia, PA, USA.
²³ Service d'Hématologie Clinique et Thérapie Cellulaire, Hôpital Saint-Antoine, Sorbonne Université, INSERM UMRs 938, Paris, France.
²⁴ Division of Hematology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
²⁵ Division of Infectious Diseases, DISSAL, University of Genova, Italy and IRCCS Ospedale Policlinico San Martino, Genova, Italy.
²⁶ Department of Transfusion Medicine and Cell Therapy, Medical University of Vienna, Vienna, Austria.
²⁷ Division of Hematology, Oncology and Transplantation, University of Minnesota, MN, USA.
²⁸ Medical University Graz, Division of Hematology, Graz, Austria.
²⁹ Haematology Department, Henri Mondor Hospital and University Paris-Est-Créteil, Créteil, France.

PMID: 36990623
DOI: 10.1016/S2352-3026(23)00032-7

Abstract

Literature discussing endemic and regionally limited infections in recipients of haematopoietic stem-cell transplantation (HSCT) outside western Europe and North America is scarce. This Worldwide Network for Blood and Marrow Transplantation (WBMT) article is part one of two papers aiming to provide guidance to transplantation centres around the globe regarding infection prevention and treatment, and considerations for transplantation based on current evidence and expert opinion. These recommendations were initially formulated by a core writing team from the WBMT and subsequently underwent multiple revisions by infectious disease experts and HSCT experts. In this paper, we summarise the data and provide recommendations on several endemic and regionally limited viral and bacterial infections, many of which are listed by WHO as neglected tropical diseases, including Dengue, Zika, yellow fever, chikungunya, rabies, brucellosis, melioidosis, and leptospirosis.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests MBK declares honoraria from Gilead and an advisory board role at Gilead. RDLC declares honoraria from Gilead. NW declares honoraria and consultancy fees from Novartis; travel and honoraria from Kite Gilead; honoraria and research funding from Sanofi Genzyme; honoraria and speaker fees from Therakos Mallinckrodt; and travel fees from BMS Celgene. EB declares honoraria Novartis, Astellas, Alexion, Gilead, MSD, Keocyt, Jazz Pharmaceuticals, and Amgen; and travel fees from Jazz Pharmaceuticals, Novartis, and Amgen. JeS declares honoraria from Alexion, Sobi, and Takeda; consultancy fees from Alexion, Sobi, and Takeda; travel fees from Sobi; and an advisory board role at Prevail Therapeutics. JaS declares honoraria from MSD, Glead, TEVA, Atara, and Takeda. DW declares research funding from FATE therapeutics: Research Funding and Incyte. SKH declares honoraria from Pfizer, Novartis, Janssen, Therakos Mallinckrodt, Sanofi, and Roche. YA declares lecture fees from Novartis, AbbVie GK, and Astellas and consultancy honoraria from Meiji Seika, JCR Pharmaceuticals, and Kyowa Kirin. PL declares honoraria from Takeda, OctaPharma, and MSD. All other authors declare no competing interests.

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- ClinicalKey
- Elsevier Science
Medical
- MedlinePlus Health Information

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Endemic or regionally limited bacterial and viral infections in haematopoietic stem-cell transplantation recipients: a Worldwide Network for Blood and Marrow Transplantation (WBMT) Review

Affiliations

Endemic or regionally limited bacterial and viral infections in haematopoietic stem-cell transplantation recipients: a Worldwide Network for Blood and Marrow Transplantation (WBMT) Review

Authors

Affiliations

Abstract

Conflict of interest statement

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical