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Case Reports
. 2023 May;71(5):319-322.
doi: 10.1007/s00106-023-01282-1. Epub 2023 Mar 31.

[Odynophagia as the first symptom of monkeypox infection]

[Article in German]
Nadja Schröder  1 , Juliane Buth  2 , Ingo Drexler  3 , Ortwin Adams  3 , Inga Tometten  3 , Maximilian Seidl  2 , Christian Rubbert  4 , Jörg Schipper  5 , Julia Kristin  5
Affiliations
Case Reports

[Odynophagia as the first symptom of monkeypox infection]

[Article in German]
Nadja Schröder et al. HNO. 2023 May.

Abstract
in English, German

A 50-year-old patient with confirmed monkeypox infection presented with odynophagia and nocturnal dyspnea. Clinically, there was a lesion on the tongue without any skin lesions and fibrinous plaques on the right tonsil with asymmetry of the palatoglossal arch. Due to a suggested abscess in the CT scan, a tonsillectomy à chaud was performed. By pan-orthopox-specific polymerase chain reaction (PCR) the monkeypox infection was also confirmed in the tonsil tissue. Isolated oral findings may represent a monkeypox infection and should be considered as a currently important differential diagnosis, especially for patients at risks.

Ein 50-jähriger Patient stellte sich mit Odynophagie und nächtlicher Dyspnoe bei einer bestätigten Affenpocken-Infektion vor. Klinisch zeigten sich eine Läsion am Zungenrand ohne Hautbefall sowie eine fibrinbelegte Tonsille mit Weichgaumenasymmetrie nach rechts. Aufgrund eines in der Computertomographie(CT)-Bildgebung gesicherten Abszesses erfolgte eine Tonsillektomie à chaud. Mittels Pan-Orthopox-spezifischer Polymerasekettenreaktion (PCR) wurde die Infektion auch im Tonsillengewebe bestätigt. Isolierte orale Befunde können eine Affenpocken-Infektion darstellen und stellen bei Risikopatienten eine aktuell wichtige Differenzialdiagnose dar.

Keywords: Lymphadenopathy; Oral lesion; Orthopoxvirus; Tonsillectomy; Tonsillitis.

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