Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1979 Feb;23(2):360-5.
doi: 10.1128/iai.23.2.360-365.1979.

Adjuvants in the induction of suppressor cells

R Neta, S B Salvin

Adjuvants in the induction of suppressor cells

R Neta et al. Infect Immun. 1979 Feb.

Abstract

The effect of different mycobacterial adjuvants on the parameters of delayed hypersensitivity was investigated in strain 13 guinea pigs. The composition of the tubercle bacilli and the type of vehicle in which the antigen was presented determined the presence and extent of suppressor cell activity. When antigen was introduced in complete Freund adjuvant, both adherent and nonadherent cells had suppressive properties, with the suppressive effect demonstrable in vitro from 1 to 5 weeks after sensitization. Suppressor activity was indicated in vivo by a reduction of delayed footpad hypersensitivity in animals presensitized with complete Freund adjuvant.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Exp Med. 1964 Jul 1;120:105-20 - PubMed
    1. Nature. 1962 Feb 24;193:789-90 - PubMed
    1. J Immunol. 1976 Nov;117(5 Pt.2):2014-20 - PubMed
    1. Cell Immunol. 1977 Oct;33(2):402-11 - PubMed
    1. J Immunol. 1973 May;110(5):1290-9 - PubMed

Publication types

LinkOut - more resources