Amitriptyline for fibromyalgia: Off-label treatment, but non-inferior to approved medication

Cheng Hsien Hung¹, Yung-Heng Lee^{2

3

4

5}, James Cheng-Chung Wei^{6

7

8

9}

Affiliations

¹ Department of Pharmacy, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan.
² Department of Orthopedics, Cishan Hospital, Ministry of Health and Welfare, Kaohsiung, Taiwan.
³ Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan.
⁴ Department of Senior Services Industry Management, Minghsin University of Science and Technology, Hsinchu, Taiwan.
⁵ Department of Recreation and Sport Management, Shu-Te University, Kaohsiung, Taiwan.
⁶ Department of Allergy, Immunology & Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan.
⁷ Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
⁸ Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.
⁹ Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.

PMID: 37002904
DOI: 10.1111/1756-185X.14618

Editorial

Amitriptyline for fibromyalgia: Off-label treatment, but non-inferior to approved medication

Cheng Hsien Hung et al. Int J Rheum Dis. 2023 Apr.

. 2023 Apr;26(4):607-608.

doi: 10.1111/1756-185X.14618.

Authors

Cheng Hsien Hung¹, Yung-Heng Lee^{2

3

4

5}, James Cheng-Chung Wei^{6

7

8

9}

Affiliations

¹ Department of Pharmacy, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan.
² Department of Orthopedics, Cishan Hospital, Ministry of Health and Welfare, Kaohsiung, Taiwan.
³ Institute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung, Taiwan.
⁴ Department of Senior Services Industry Management, Minghsin University of Science and Technology, Hsinchu, Taiwan.
⁵ Department of Recreation and Sport Management, Shu-Te University, Kaohsiung, Taiwan.
⁶ Department of Allergy, Immunology & Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan.
⁷ Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan.
⁸ Graduate Institute of Integrated Medicine, China Medical University, Taichung, Taiwan.
⁹ Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.

PMID: 37002904
DOI: 10.1111/1756-185X.14618

No abstract available

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Comment on

Comparison of Amitriptyline and US Food and Drug Administration-Approved Treatments for Fibromyalgia: A Systematic Review and Network Meta-analysis.
Farag HM, Yunusa I, Goswami H, Sultan I, Doucette JA, Eguale T. Farag HM, et al. JAMA Netw Open. 2022 May 2;5(5):e2212939. doi: 10.1001/jamanetworkopen.2022.12939. JAMA Netw Open. 2022. PMID: 35587348 Free PMC article.

References

REFERENCES

1. Queiroz LP. Worldwide epidemiology of fibromyalgia. Curr Pain Headache Rep. 2013;17(8):356. doi:10.1007/s11916-013-0356-5
1. Ma KS, Lai JN, Veeravalli JJ, Chiu LT, Van Dyke TE, Wei JC. Fibromyalgia and periodontitis: bidirectional associations in population-based 15-year retrospective cohorts. J Periodontol. 2022;93(6):877-887. doi:10.1002/jper.21-0256
1. Gau SY, Leong PY, Lin CL, Tsou HK, Wei JC. Higher risk for Sjögren's syndrome in patients with fibromyalgia: a nationwide population-based cohort study. Front Immunol. 2021;12:640618. doi:10.3389/fimmu.2021.640618
1. Gau SY, Lee YH, Tsou HK, et al. Patients with ankylosing spondylitis are associated with high risk of fibromyalgia: a nationwide population-based cohort study. Front Med (Lausanne). 2021;8:618594. doi:10.3389/fmed.2021.618594
1. Macfarlane GJ, Kronisch C, Dean LE, et al. EULAR revised recommendations for the management of fibromyalgia. Ann Rheum Dis. 2017;76(2):318-328. doi:10.1136/annrheumdis-2016-209724

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Amitriptyline for fibromyalgia: Off-label treatment, but non-inferior to approved medication

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Amitriptyline for fibromyalgia: Off-label treatment, but non-inferior to approved medication

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