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. 1986 Apr;60(4):1446-50.
doi: 10.1152/jappl.1986.60.4.1446.

Effects of pressure on uptake and release of calcium by brain synaptosomes

S C Gilman, K K Kumaroo, J M Hallenbeck

Effects of pressure on uptake and release of calcium by brain synaptosomes

S C Gilman et al. J Appl Physiol (1985). 1986 Apr.

Abstract

Uptake of radioactive calcium from guinea pig brain fractions enriched in synaptosomes could be significantly and reproducibly decreased by exposure to high pressure. Calcium efflux from preloaded synaptosomes was unaffected by pressure exposure. It was hypothesized that the development of pressure-induced encephalopathy may be related to an effect of pressure on the central nervous system calcium transport system.

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