Molnupiravir efficacy among immunocompromised patients with COVID-19: no proof of concept
- PMID: 37004695
- PMCID: PMC10066965
- DOI: 10.1007/s15010-023-02027-6
Molnupiravir efficacy among immunocompromised patients with COVID-19: no proof of concept
Conflict of interest statement
DF has received research support from Viracor, Astellas and Merck, and consultant fee from Viracor. All other authors have nothing to disclose.
Comment on
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Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled MOVe-OUT trial.Infection. 2023 Oct;51(5):1273-1284. doi: 10.1007/s15010-022-01959-9. Epub 2023 Jan 17. Infection. 2023. PMID: 36648627 Free PMC article. Clinical Trial.
References
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- Johnson MG, Strizki JM, Brown ML, Wan H, Shamsuddin HH, Ramgopal M, et al. Molnupiravir for the treatment of COVID-19 in immunocompromised participants: efficacy, safety, and virology results from the phase 3 randomized, placebo-controlled MOVe-OUT trial. Infection. 2023 doi: 10.1007/s15010-022-01959-9. - DOI - PMC - PubMed
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- Gleeson S, Martin P, Thomson T, et al. Kidney transplant recipients and omicron: outcomes, effect of vaccines and the efficacy and safety of novel treatments. medRxiv. 2022 doi: 10.1101/2022.05.03.22274524. - DOI
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- Butler CC, Hobbs FDR, Gbinigie OA, Rahman NM, Hayward G, Richards DB, et al. Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial. Lancet. 2023;401:281–293. doi: 10.1016/S0140-6736(22)02597-1. - DOI - PMC - PubMed
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