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Case Reports
. 2023 Mar 20;10(3):ofad145.
doi: 10.1093/ofid/ofad145. eCollection 2023 Mar.

Headaches in a Horseback Rider

Affiliations
Case Reports

Headaches in a Horseback Rider

Nicole Hunter et al. Open Forum Infect Dis. .

Abstract

An immunocompetent woman presented with headaches. She previouslyworked at a farm in upstate New York. Brain MRI noted pituitary enlargement and neurosurgerypursued trans-sphenoidal pituitary biopsy. Histopathology revealed ill-defined granulomaswith clusters of yeast, consistent with Histoplasma.

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Conflict of interest statement

Potential conflicts of interest. All authors: No reported conflicts.

Figures

Figure 1.
Figure 1.
Pituitary MRI revealed an enlarged pituitary measuring 1.4 × 0.7 × 1.1 cm on sagittal view, indicated by the white arrow. Abbreviations: AR, anterior; F, feet; H, head; PL, posterior.
Figure 2.
Figure 2.
Ill-defined granulomas and clusters of small extracellular (white arrows) and intracellular yeast forms seen on Gomori methenamine silver (A) and periodic acid-Schiff (B) stains.

References

    1. Azar MM, Loyd JL, Relich RF, Wheat LJ, Hage CA. Current concepts in the epidemiology, diagnosis, and management of histoplasmosis syndromes. Semin Respir Crit Care Med 2020; 41:13–30. - PubMed
    1. Araúz AB, Papineni P. Histoplasmosis. Infect Dis Clin North Am 2021; 35:471–91. - PubMed
    1. Mazi PB, Sahrmann JM, Olsen MA, et al. . The geographic distribution of dimorphic mycoses in the United States for the modern era [manuscript published online ahead of print 11 November 2022]. Clin Infect Dis 2022. doi:10.1093/cid/ciac882 - DOI - PMC - PubMed
    1. Horwath MC, Fecher RA, Deepe GS Jr. Histoplasma capsulatum, lung infection and immunity. Future Microbiol 2015; 10:967–75. - PMC - PubMed
    1. Adenis AA, Aznar C, Couppié P. Histoplasmosis in HIV-infected patients: a review of new developments and remaining gaps. Curr Trop Med Rep 2014; 1:119–28. - PMC - PubMed

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