Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Mar 4:7:110-115.
doi: 10.1016/j.ijregi.2023.02.011. eCollection 2023 Jun.

Prevalence of HPV infection among Thai schoolgirls in the north-eastern provinces in 2018: implications for HPV immunization policy

Sompong Vongpunsawad  1 , Chulwoo Rhee  2 , Pornjarim Nilyanimit  1 , Nimesh Poudyal  2 , Suchada Jiamsiri  3 , Hyeon Seon Ahn  2 , Jinae Lee  2 , Hyeong-Won Seo  2 , Worrawan Klinsupa  3 , Sunju Park  2 , Nakorn Premsri  4 , Chawetsan Namwat  3 , Patummal Silaporn  3 , Jean-Louis Excler  2 , Deok-Ryun Kim  2 , Lauri E Markowitz  5 , Elizabeth R Unger  5 , Supachai Rerks-Ngarm  3 , Julia Lynch  2 , Yong Poovorawan  1
Affiliations

Prevalence of HPV infection among Thai schoolgirls in the north-eastern provinces in 2018: implications for HPV immunization policy

Sompong Vongpunsawad et al. IJID Reg. .

Abstract

Objective: The aim of this study was to determine the prevalence of high-risk (HR) and vaccine-type human papillomavirus (HPV) infection among Thai schoolgirls who were not included in the national HPV immunization program.

Methods: Cross-sectional surveys were conducted among grade 10 (15-16 years old) and grade 12 (17-18 years old) schoolgirls in two provinces of Thailand. Urine samples were collected using the Colli-PeeⓇ device from November 2018 to February 2019. The samples were initially tested using CobasⓇ 4800. Subsequently, all Cobas-positive samples and 1:1 matched Cobas-negative samples were tested by AnyplexⓇ assay. Prevalences of any HPV, any HR HPV, vaccine-type HPV, and individual HR HPV types were estimated by school grade.

Results: Prevalences of any HPV and any HR HPV were 11.6% and 8.6% for grade 10, and 18.5% and 12.4% for grade 12 schoolgirls, respectively. Prevalences of bivalent vaccine-type HPV infection in grades 10 and 12 were 3.4% and 4.5%, respectively. Prevalences of quadrivalent and nonavalent vaccine-type HPV infections were 4.0%/6.6% and 6.4%/10.4% in grades 10 and 12, respectively. HPV16 was the most common type detected, followed by HPV58, 51, and 52. Circulating HR HPV types were similar between the school grades.

Conclusion: A substantial burden of HR HPV infections was found among unvaccinated high school girls in Thailand.

Keywords: Thailand; genotype distribution; human papillomavirus; prevalence.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Consort diagram for subjects enrolled in 2018 cross-sectional survey.
Figure 2
Figure 2
Weighted prevalences of any HPV, any high-risk HPV, and one or more vaccine-type HPV infections by school grade.
Figure 3
Figure 3
Weighted prevalences of high-risk HPV types, by school grade.
Figure 4
Figure 4
Prevalences of single and multiple high-risk HPV infections, by school type and grade.
See this image and copyright information in PMC

References

    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71:209–249. - PubMed
    1. Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol. 1999;189(1):12–19. - PubMed
    1. Gravitt PE, Winer RL. Natural history of HPV infection across the lifespan: role of viral latency. Viruses. 2017;9(10):267. doi: 10.3390/v9100267. - DOI - PMC - PubMed
    1. Sanjosé S, Brotons M, Pavón MA. The natural history of human papillomavirus infection. Best Pract Res Clin Obstet Gynaecol. 2018;47:2–13. - PubMed
    1. Koshiol J, Lindsay L, Pimenta JM, Poole C, Jenkins D, Smith JS. Persistent human papillomavirus infection and cervical neoplasia: a systematic review and meta-analysis. Am J Epidemiol. 2008;168(2):123–137. - PMC - PubMed

LinkOut - more resources