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Meta-Analysis
. 2023 Mar;8(2):114-124.
doi: 10.14744/eej.2023.88528.

Effect of Endodontic Irrigation on Mineral Content of Root Canal Dentine: A Systematic Review and Meta-Analysis

Ezatolah Kazeminejad  1 , Milad Niazi  2 , Ensieh Geraili  1 , Abdolhalim Rajabi  3 , Masoud Mohammadi  4
Affiliations
Meta-Analysis

Effect of Endodontic Irrigation on Mineral Content of Root Canal Dentine: A Systematic Review and Meta-Analysis

Ezatolah Kazeminejad et al. Eur Endod J. 2023 Mar.

Abstract

A systematic review and meta-analysis were conducted to evaluate the effect of endodontic irrigation on the mineral content of root canal dentine. A systematic search was performed in the following databases: PubMed, Web of Science, Scopus, Cochrane, ProQuest, and Wiley. The quality assessment of the articles was performed. The meta-analysis was carried out using the random effects model in the Stata 16 software (p<0.05). The results showed that Er: YAG Laser had a significant effect on the removal of the phosphorus content of dentine (Hedges' g=-0.49; 95% CI: -0.85, -0.13; I2=0.0%). In addition, the EDTA 5Min had a lower removal effect compared to the control group on the magnesium content of dentine (Hedges' g=0.58; 95% CI: 0.00, 1.16; I2=0.0%). Other irrigations had no significant effect on other on the mineral content of root canal dentine. Evidence was found to support that most root canal irrigation protocols did not have a significantly affected in terms of the mineral content of root dentine. (EEJ-2022-11-140).

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Conflict of interest statement

The authors deny any conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of study selection procedure and exclusion criteria
Figure 2
Figure 2
Forest plot of effect of endodontic irrigation on the calcium content of root canal dentine. (a) For Chlorhexidine (CHX), (b) For 5.25% NaOCl, (c) For 2.5% NaOCl, (d) For Nd:YAG laser, (e) For Er:YAG laser, (f) For Ethylenediaminetetraacetic acid (EDTA)
Figure 3
Figure 3
Forest plot of effect of endodontic irrigation on the phosphorus content of root canal dentine. (a) For Chlorhexidine (CHX), (b) For 5.25% NaOCl, (c) For 2.5% NaOCl, (d) For Nd:YAG laser, (e) For Er:YAG laser, (f) For Ethylenediaminetetraacetic acid (EDTA)
Figure 4
Figure 4
Forest plot of effect of endodontic irrigation on the magnesium content of root canal dentine. (a) For 5.25% NaOCl, (b) For Chlorhexidine (CHX), (c) For 2.5% NaOCl, (d) For Nd:YAG laser, (e) For Er:YAG laser, (f) For Ethylenediaminetetraacetic acid (EDTA)
Figure 5
Figure 5
Forest plot of effect of endodontic irrigation on the calcium to phosphorus ratio content of root canal dentine. (a) For Nd:YAG laser, (b) For Er:YAG laser
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